Revisiting 5α-reductase inhibitors and the risk of prostate cancer

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作者
Cindy H. Chau
William D. Figg
机构
[1] National Cancer Institute,Genitourinary Malignancies Branch, Center for Cancer Research
[2] National Institutes of Health,undefined
来源
Nature Reviews Urology | 2018年 / 15卷
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摘要
The role of 5α-reductase inhibitors (5-ARI) in prostate cancer chemoprevention remains a controversy, as cancer prevention trials with 5-ARIs have shown a decreased incidence of low-grade prostate cancer but a potential increased risk in high-grade disease. Recent studies have shed light on the long-term safety of 5-ARIs in terms of influencing prostate cancer risk.
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页码:400 / 401
页数:1
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