Ultrasound-Assisted and One-Pot Synthesis of New Fe3O4/Mo-MOF Magnetic Nano Polymer as a Strong Antimicrobial Agent and Efficient Nanocatalyst in the Multicomponent Synthesis of Novel Pyrano[2,3-d]pyrimidines Derivatives

被引:0
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作者
Tarik Hafdhi Abdtawfeeq
Zainab A. Farhan
Kadhum Al-Majdi
Mohammed Abed Jawad
Rahman S. Zabibah
Yassine Riadi
Salema K. Hadrawi
Ameen AL-Alwany
Marwah A. Shams
机构
[1] Al-Farahidi University,Medical Technical College
[2] Al-Mustaqbal University College,Air conditioning and Refrigeration Techniques Engineering Department
[3] Ashur University College,Department of Biomedical Engineering
[4] Al-Nisour University College,Medical Laboratory Technology Department, College of Medical Technology
[5] The Islamic University,Department of Pharmaceutical Chemistry, College of Pharmacy
[6] Prince Sattam Bin Abdulaziz University,Refrigeration and Air
[7] The Islamic University,conditioning Technical Engineering Department, College of Technical Engineering
[8] University of Baghdad,College of Medicine
[9] Technical Engineering College,undefined
[10] Al-Ayen University,undefined
关键词
Ultrasound-assisted; Metal–organic framework; Fe; O; /Mo-MOF; Core shell nanoparticles; Magnetic nanocatalyst; Pyrano[2,3-d]pyrimidines; Antimicrobial properties;
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学科分类号
摘要
A new Fe3O4/Mo-MOF (metal–organic framework) magnetic nano polymer was synthesized in one step and Ultrasound assisted. Fe3O4/Mo-MOF magnetic nano polymer was characterized by XRD, SEM, EDX mapping BET, VSM, and FT-IR. The results of the structure confirmation revealed that the ultrasonic method had created unique properties in the Fe3O4/Mo-MOF magnetic nano polymer, and its biological and catalytic applications were investigated. A new pyrano[2,3-d]pyrimidines derivative was synthesized using the catalytic activity of Fe3O4/Mo-MOF magnetic nano polymer in a three-component reaction involving malononitrile, aldehyde derivatives, and barbituric acid derivatives with Fe3O4/Mo-MOF magnetic nano polymer as a magnetic catalyst. In the antimicrobial activity of Fe3O4/Mo-MOF magnetic nano polymer: Antimicrobial properties on gram-positive, gram-negative, and fungal strains based on MIC, MBC, and MFC value. The results of catalytic and biological studies proved that nanoparticles have unique properties attributed to their structure and synthesis method.
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页码:472 / 483
页数:11
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