Hyperthermic Isolated Limb Perfusion With Tumor Necrosis Factor-α and Melphalan in Advanced Soft-Tissue Sarcomas: Histopathological Considerations

被引:0
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作者
Josephine Issakov
Ofer Merimsky
Mordechai Gutman
Yehuda Kollender
Dina Lev-Chelouche
Soubhi Abu-Abid
Beatriz Lifschitz-Mercer
Moshe Inbar
Joseph M. Klausner
Isaac Meller
机构
[1] Tel-Aviv Sourasky Medical Center,Department of Pathology and Unit of Bone and Soft Tissue Pathology
[2] Affiliated with Sackler Faculty of Medicine,Departments of Oncology
[3] Tel-Aviv University,Departments of Surgery
[4] Tel-Aviv Sourasky Medical Center Affiliated with Sackler Faculty of Medicine,National Unit of Orthopedic Oncology
[5] Tel-Aviv University,undefined
[6] Tel-Aviv Sourasky Medical Center Affiliated with Sackler Faculty of Medicine,undefined
[7] Tel-Aviv University,undefined
[8] Tel-Aviv Sourasky Medical Center Affiliated with Sackler Faculty of Medicine,undefined
[9] Tel-Aviv University,undefined
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关键词
TNF-α; Isolated limb perfusion; Soft-tissue sarcoma; Neoadjuvant treatment.;
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摘要
Background: Hyperthermic isolated limb perfusion with tumor necrosis factor-α and melphalan was used as induction treatment in locally advanced extremity soft-tissue sarcomas for limb sparing surgery. The typical histopathological changes that occur in these tumoral masses are described in a series of 30 patients.
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页码:155 / 159
页数:4
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