Defying death: showing Bcl-2 the way home

被引：0
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作者：
Colin Adrain
Emma M. Creagh
Seamus J. Martin
机构：
[1] Molecular Cell Biology Laboratory,Department of Genetics
[2] Trinity College,undefined
来源：
Nature Cell Biology | 2003年 / 5卷
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摘要：
Bcl-2 and Bcl-xL perform important functions in cell life or death decisions by setting the threshold for activation of the programmed cell death machinery. FKBP38, a member of the immunophilin family, has now been identified as a new Bcl-2/Bcl-xL-binding partner. Furthermore, FKBP38 seems to be crucial in targeting Bcl-2/Bcl-xL to the correct cellular locations.
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页码：9 / 11
页数：2
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