Cytolytic activity correlates with the mutational burden and deregulated expression of immune checkpoints in colorectal cancer

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作者
Apostolos Zaravinos
Constantinos Roufas
Majdi Nagara
Beatriz de Lucas Moreno
Maria Oblovatskaya
Christodoulos Efstathiades
Christos Dimopoulos
Georgios D. Ayiomamitis
机构
[1] European University Cyprus,Department of Life Sciences, School of Sciences
[2] Centre for Risk and Decision Sciences (CERIDES),Department of Computer Science & Engineering
[3] European University Cyprus,Inserm, UMR
[4] Aix Marseille University,S 1251, MMG, Faculté de Médecine
[5] European University Madrid,Center for Research in Health and Life Sciences
[6] Tzaneion General Hospital,1st Surgical Department
关键词
Colorectal cancer; Cytolytic activity; Classically defined neoepitopes; Alternatively defined neoepitopes; Mutation burden; Immune checkpoints; Cancer drivers;
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