Reduction in pericyte coverage leads to blood–brain barrier dysfunction via endothelial transcytosis following chronic cerebral hypoperfusion

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作者
Zhengyu Sun
Chenhao Gao
Dandan Gao
Ruihua Sun
Wei Li
Fengyu Wang
Yanliang Wang
Huixia Cao
Guoyu Zhou
Jiewen Zhang
Junkui Shang
机构
[1] Henan Provincial People’s Hospital,Department of Neurology
[2] Zhengzhou University People’s Hospital,Department of Nephrology, Henan Provincial Key Laboratory of Kidney Disease and Immunology
[3] Henan University People’s Hospital,School of Public Health
[4] Henan Provincial People’s Hospital,undefined
[5] Zhengzhou University People’s Hospital,undefined
[6] Henan University People’s Hospital,undefined
[7] Zhengzhou University,undefined
关键词
Cerebral small vessel disease; Chronic cerebral hypoperfusion; BBB permeability; BBB protection; Pericyte; Endothelial transcytosis; White matter lesions; TGF-β signaling;
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