Vascular calcification is associated with an increased risk of cardiovascular and all-cause mortality. In the past decade, the prevalence, significance, and regulatory mechanisms of vascular calcification have gained increasing recognition. In this Review, Drs. Sage, Tintut and Demer discuss our knowledge of the regulatory mechanisms for both atherosclerotic and medial calcification.
机构:
Brigham & Womens Hosp, Div Cardiovasc Med, Boston, MA 02115 USA
Harvard Univ, Sch Med, Boston, MA 02115 USABrigham & Womens Hosp, Div Cardiovasc Med, Boston, MA 02115 USA