Simvastatin abrogates inflamed neutrophil adhesive properties, in association with the inhibition of Mac-1 integrin expression and modulation of Rho kinase activity

被引:0
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作者
Angélica Aparecida Antoniellis Silveira
Venina Marcela Dominical
Mariana Lazarini
Fernando Ferreira Costa
Nicola Conran
机构
[1] School of Medicine,INCT de Sangue, Hematology and Hemotherapy Center
[2] University of Campinas-UNICAMP,Hemocentro
[3] Rua Carlos Chagas,undefined
[4] 480,undefined
[5] Cidade Universitária,undefined
来源
Inflammation Research | 2013年 / 62卷
关键词
Adhesion; Inflammation; Neutrophil; Statin; Rho GTPase;
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页码:127 / 132
页数:5
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  • [1] Simvastatin abrogates inflamed neutrophil adhesive properties, in association with the inhibition of Mac-1 integrin expression and modulation of Rho kinase activity
    Antoniellis Silveira, Angelica Aparecida
    Dominical, Venina Marcela
    Lazarini, Mariana
    Costa, Fernando Ferreira
    Conran, Nicola
    [J]. INFLAMMATION RESEARCH, 2013, 62 (02) : 127 - 132
  • [2] Expression, activation, and function of integrin αMβ2 (Mac-1) on neutrophil-derived microparticles
    Pluskota, Elzbieta
    Woody, Neil M.
    Szpak, Dorota
    Ballantyne, Christie M.
    Soloviev, Dmitry A.
    Simon, Daniel I.
    Plow, Edward F.
    [J]. BLOOD, 2008, 112 (06) : 2327 - 2335
  • [3] Endoplasmic Reticulum Protein 72 Regulates Integrin Mac-1 Activity to Influence Neutrophil Recruitment
    Li, Yaofeng
    Xu, Xulin
    Wang, Haoqing Jerry
    Chen, Yiyao Catherine
    Chen, Yaobing
    Chiu, Joyce
    Li, Li
    Wang, Lei
    Wang, Jinyu
    Tang, Zhaoming
    Ren, Lehao
    Li, Hongliang
    Wang, Xuanbin
    Jin, Si
    Wu, Yi
    Huang, Mingdong
    Ju, Lining Arnold
    Fang, Chao
    [J]. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2024, 44 (03) : E82 - E98
  • [4] INDUCTION OF NEUTROPHIL MAC-1 INTEGRIN EXPRESSION AND SUPEROXIDE PRODUCTION BY THE MEDICINAL PLANT-EXTRACT GOSSYPOL
    BENHAIM, P
    MATHES, SJ
    HUNT, TK
    SCHEUENSTUHL, H
    BENZ, CC
    [J]. INFLAMMATION, 1994, 18 (05) : 443 - 458
  • [5] β2-agonist-induced inhibition of neutrophil chemotaxis is not associated with modification of LFA-1 and Mac-1 expression or with impairment of polymorphonuclear leukocyte antibacterial activity
    Silvestri, M
    Oddera, S
    Lantero, S
    Rossi, GA
    [J]. RESPIRATORY MEDICINE, 1999, 93 (06) : 416 - 423
  • [6] Methylprednisolone induced neutrophil leukocytosis down modulation of neutrophil L-selectin and Mac-1 expression and induction of granulocyte-colony stimulating factor
    Crockard, AD
    Boylan, MT
    Droogan, AG
    McMillan, SA
    Hawkins, SA
    [J]. INTERNATIONAL JOURNAL OF CLINICAL & LABORATORY RESEARCH, 1998, 28 (02): : 110 - 115
  • [7] RHO-KINASE SIGNALING REGULATES PULMONARY INFILTRATION OF NEUTROPHILS IN ABDOMINAL SEPSIS VIA ATTENUATION OF CXC CHEMOKINE FORMATION AND MAC-1 EXPRESSION ON NEUTROPHILS
    Hasan, Zirak
    Palani, Karzan
    Rahman, Milladur
    Zhang, Su
    Syk, Ingvar
    Jeppsson, Bengt
    Thorlacius, Henrik
    [J]. SHOCK, 2012, 37 (03): : 282 - 288
  • [8] Inhibition of tyrosine kinase activity prevents the adhesive and cohesive properties of platelets and the expression of procoagulant activity in response to collagen
    Diaz-Ricart, Maribel
    Palomo, Marta
    Fuste, Berta
    Lopez-Vilchez, Irene
    Carbo, Carla
    Perez-Pujol, Silvia
    White, James G.
    Escolar, Gines
    [J]. THROMBOSIS RESEARCH, 2008, 121 (06) : 873 - 883
  • [9] Concentration-dependent activity of mometasone furoate and dexamethasone on blood eosinophils isolated from atopic children: modulation of Mac-1 expression and chemotaxis
    Sale, R
    Sabatini, F
    Silvestri, M
    Serpero, L
    Petecchia, L
    Rossi, GA
    [J]. INTERNATIONAL IMMUNOPHARMACOLOGY, 2004, 4 (13) : 1687 - 1696
  • [10] Soluble CD40 Ligand Stimulates CD40-Dependent Activation of the β2 Integrin Mac-1 and Protein Kinase C Zeda (PKCζ) in Neutrophils: Implications for Neutrophil-Platelet Interactions and Neutrophil Oxidative Burst
    Jin, Rong
    Yu, Shiyong
    Song, Zifang
    Zhu, Xiaolei
    Wang, Cuiping
    Yan, Jinchuan
    Wu, Fusheng
    Nanda, Anil
    Granger, D. Neil
    Li, Guohong
    [J]. PLOS ONE, 2013, 8 (06):