Hyaluronic acid and silver sulfadiazine-impregnated polyurethane foams for wound dressing application

被引：0
|
作者：
Y.-S. Cho
J.-W. Lee
J.-S. Lee
J. H. Lee
T. R. Yoon
Y. Kuroyanagi
M. H. Park
H. J. Kim
机构：
[1] Kwangju Institute of Science and Technology (K-JIST),Department of Materials Science and Engineering
[2] Hannam University,Department of Polymer Science and Engineering
[3] Chonnam University Hospital,Department of Orthopedics
[4] Kitasato University,R & D Center for Artificial Skin, School of Allied Health Sciences
[5] Biopol Co. Ltd.,undefined
来源：
Journal of Materials Science: Materials in Medicine | 2002年 / 13卷
关键词：
Foam; Alginate; Drug Release; Polyurethane; Hyaluronic Acid;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Five different kinds of PU foam wound dressings were prepared to investigate their wound healing capability. They include (i) PU+silver sulfadiazine (AgSD), (ii) PU+alginate (Al), (iii) PU+Al+AgSD, (iv) PU+hyaluronic acid (HA), and (v) PU+HA+AgSD. Physical properties and in vitro behaviors of AgSD release and fibroblast adhesion on those dressings were evaluated. From the drug release and fibroblast adhesion studies, it was observed that PU foam impregnated with both HA and AgSD shows good drug release behavior and low adhesion of the cells. Furthermore, the HA and AgSD-containing PU foam showed excellent wound healing effect without any inflammation or yellow cluster. The wound size decreased around 77% after 1 week application of that foam dressing onto a rat skin defect.
引用
收藏
页码：861 / 865
页数：4
相关论文
共 50 条
  • [1] Hyaluronic acid and silver sulfadiazine-impregnated polyurethane foams for wound dressing application
    Cho, YS
    Lee, JW
    Lee, JS
    Lee, JH
    Yoon, TR
    Kuroyanagi, Y
    Park, MH
    Kim, HJ
    [J]. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 2002, 13 (09) : 861 - 865
  • [2] Chlorhexidine-silver sulfadiazine-impregnated venous catheters save costs
    Lorente, Leonardo
    Lecuona, Maria
    Jimenez, Alejandro
    Santacreu, Ruth
    Raja, Lorena
    Gonzalez, Oswaldo
    Mora, Maria L.
    [J]. AMERICAN JOURNAL OF INFECTION CONTROL, 2014, 42 (03) : 321 - 324
  • [3] Silver Sulfadiazine-Impregnated Hydrocolloid Dressing Is Beneficial in Split-Thickness Skin-Graft Donor Wound Healing in a Small Randomized Controlled Study
    Akita, Sadanori
    Yoshimoto, Hiroshi
    Tanaka, Katsuya
    Oishi, Masao
    Senju, Chikako
    Mawatari, Seiji
    Takahara, Eisaku
    Suzuki, Sizuka
    Hayashida, Kenji
    [J]. INTERNATIONAL JOURNAL OF LOWER EXTREMITY WOUNDS, 2016, 15 (04): : 338 - 343
  • [4] Electrospun polyvinylidene pyrolidone/gelatin membrane impregnated with silver sulfadiazine as wound dressing for burn treatment
    Semnani, Dariush
    Poursharifi, Nazanin
    Banitaba, Nooshin
    Fakhrali, Aref
    [J]. BULLETIN OF MATERIALS SCIENCE, 2018, 41 (03)
  • [5] Electrospun polyvinylidene pyrolidone/gelatin membrane impregnated with silver sulfadiazine as wound dressing for burn treatment
    Dariush Semnani
    Nazanin Poursharifi
    Nooshin Banitaba
    Aref Fakhrali
    [J]. Bulletin of Materials Science, 2018, 41
  • [6] Efficiency of chlorhexidine-silver sulfadiazine-impregnated venous catheters at subclavian sites
    Lorente, Leonardo
    Lecuona, Maria
    Jimenez, Alejandro
    Lorenzo, Lisset
    Santacreu, Ruth
    Ramos, Silvia
    Hurtado, Eva
    Buitrago, Manuel
    Mora, Maria L.
    [J]. AMERICAN JOURNAL OF INFECTION CONTROL, 2015, 43 (07) : 711 - 714
  • [7] Chitosan/Polyurethane Blended Fiber Sheets Containing Silver Sulfadiazine for Use as an Antimicrobial Wound Dressing
    Lee, Sang Jin
    Heo, Dong Nyoung
    Moon, Ji-Hoi
    Park, Ha Na
    Ko, Wan-Kyu
    Bae, Min Soo
    Lee, Jung Bok
    Park, Se Woong
    Kim, Eun-Cheol
    Lee, Chang Hoon
    Jung, Bock-Young
    Kwon, Il Keun
    [J]. JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, 2014, 14 (10) : 7488 - 7494
  • [8] Effectiveness of Minocycline/Rifampin vs Chlorhexidine/Silver Sulfadiazine-Impregnated Central Venous Catheters
    Mermel, Leonard A.
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 2015, 221 (04) : 891 - 892
  • [9] Comparison of silver nylon wound dressing and silver sulfadiazine in partial burn wound therapy
    Abedini, Fereydoon
    Ahmadi, Abdollah
    Yavari, Akram
    Hosseini, Vahid
    Mousavi, Sarah
    [J]. INTERNATIONAL WOUND JOURNAL, 2013, 10 (05) : 573 - 578
  • [10] Silver sulfadiazine loaded chitosan/chondroitin sulfate films for a potential wound dressing application
    Fajardo, Andre R.
    Lopes, Lais C.
    Caleare, Angelo O.
    Britta, Elizandra A.
    Nakamura, Celso V.
    Rubira, Adley F.
    Muniz, Edvani C.
    [J]. MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2013, 33 (02): : 588 - 595
12345