Dynamic contrast-enhanced MR evaluation of prostate cancer before and after endorectal high-intensity focused ultrasound [La risonanza magnetica perfusionale nella valutazione dell'adenocarcinoma della prostata prima e dopo HIFU transrettale]

被引：0

作者：

Del Vescovo R. ^{[1
]}

Pisanti F. ^{[2
]}

Russo V. ^{[3
]}

Battisti S. ^{[1
]}

Cazzato R.L. ^{[1
]}

D'Agostino F. ^{[1
]}

Giurazza F. ^{[1
]}

Quattrocchi C.C. ^{[1
]}

Faiella E. ^{[1
]}

Setola R. ^{[3
]}

Giulianelli R. ^{[2
]}

Grasso R.F. ^{[1
]}

Beomonte Zobel B. ^{[1
]}

机构：

[1] Department of Radiology, Campus Bio-Medico, University of Rome, Rome

[2] Department of Urology, Villa Tiberia, Rome

[3] Interdisciplinary Center for Biomedical Research, Campus Bio-Medico, University of Rome, Rome

来源：

La radiologia medica | 2013年 / 118卷 / 5期

关键词：

D-CE-MR; DYCHO; HIFU; MRI; Prostate cancer;

D O I：

10.1007/s11547-012-0876-9

中图分类号：

学科分类号：

摘要：

Purpose: The authors sought to determine the diagnostic performance of dynamic contrast-enhanced magnetic resonance (DCE-MR) imaging in the evaluation of prostate cancer before and after transrectal high-intensity focused ultrasound (HIFU) treatment. Materials and methods: We analysed 25 patients with prostate cancer. The prostate-specific antigen (PSA) value was evaluated 1, 4 and 6 months after treatment. DCE-MR imaging was performed the day prior to and 1, 4 and 6 months after HIFU treatment. Transrectal prostate biopsies were obtained at the time of diagnosis and 6 months after treatment. Results: Before treatment, intraglandular lesions were considered to be potential sites of neoplasm and subsequently confirmed as sites of prostate adenocarcinoma in all 25 patients based on prostatespecific antigen (PSA) values and histological examinations (rho=1; p<0.001). Using histology as the gold standard, DCE-MR imaging displayed 100% sensitivity, 100% specificity, 100% positive predictive value and 100% negative predictive value before treatment. After HIFU treatment, DCE-MR imaging showed 100% sensitivity and 96% specificity. Conclusions: DCE-MR imaging can be used to visualise prostate adenocarcinoma. Several morphological and postgadolinium modifications in the follow-up DCE-MR images after HIFU treatment were also observed. © 2012 Springer-Verlag Italia.

引用

页码：851 / 862

页数：11

共 2 条

[1] Dynamic contrast-enhanced MR evaluation of prostate cancer before and after endorectal high-intensity focused ultrasound
Del Vescovo, R.
Pisanti, F.
Russo, V.
Battisti, S.
Cazzato, R. L.
D'Agostino, F.
Giurazza, F.
Quattrocchi, C. C.
Faiella, E.
Setola, R.
Giulianelli, R.
Grasso, R. F.
Zobel, B. Beomonte
RADIOLOGIA MEDICA, 2013, 118 (05): : 851 - 862
[2] MR imaging of rectal cancer before and after chemoradiation therapy [La risonanza magnetica nella valutazione dell'adenocarcinoma del retto prima e dopo trattamento chemio-radioterapico]
Del Vescovo R.
Trodella L.E.
Sansoni I.
Cazzato R.L.
Battisti S.
Giurazza F.
Ramella S.
Cellini F.
Grasso R.F.
Trodella L.
Beomonte Zobel B.
La radiologia medica, 2012, 117 (7) : 1125 - 1138

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