TANGOing along the protein secretion pathway

被引:0
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作者
Catherine Rabouille
Vangelis Kondylis
机构
[1] University Medical Center Utrecht,Department of Cell Biology and Institute of Biomembranes
[2] The Cell Microscopy Center,undefined
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关键词
Secretory Pathway; Golgi Membrane; Anterograde Transport; Golgi Stack; Exocytic Pathway;
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摘要
Although the organization and functions of the constitutive secretory pathway have been intensively studied for decades, a recent genome-wide RNAi screen in Drosophila cells has identified about 100 genes encoding novel so-called TANGO proteins (for transport and Golgi organization) that may be direct regulators of various aspects of protein exocytosis or secretion.
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