Effect of amiridine on conditioned reflex in rats with damaged hippocampus

被引：0
|
作者：
T. A. Mering
E. N. Kuleshova
I. V. Viktorov
Yu. V. Burov
机构：
[1] Russian Academy of Medical Sciences,Laboratory for Morphophysiology of Conditioned Reflexes, Institute of Brain Research
[2] All-Russian Research Center for Safety of Biologically Active Substances,Laboratory of Psychoneuropharmacology
[3] Staraya Kupavna,undefined
来源：
Bulletin of Experimental Biology and Medicine | 1997年 / 123卷
关键词：
amiridine; quinolinic acid; conditioned reflex to time; spatiotemporal differentiations; hippocampal damage;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
It is shown that even after partial damage to the hippocampus in male rats by quinolinic acid, which causes selective degeneration of hippocampal neurons, their conditioned reflex to time remains impaired for a period of several months. Treatment with amiridine improves the learning of time-interval estimation by such rats and promotes compensatory/restorative processes in the brain. The brain contains a great diversity of connections, and their stimulation may offer an opportunity for enhancing the operation of compensatory/restorative mechanisms in it.
引用
收藏
页码：147 / 150
页数：3
相关论文
共 50 条
  • [1] Effect of amiridine on conditioned reflex in rats with damaged hippocampus
    Mering, TA
    Kuleshova, EN
    Viktorov, IV
    Burov, YV
    BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 1997, 123 (02) : 147 - 150
  • [2] ULTRASTRUCTURE OF HIPPOCAMPUS NEURONS IN ELABORATION OF CONDITIONED REFLEX IN RATS
    TUSHMALO.NA
    PROKOFEV.LI
    ZHURNAL VYSSHEI NERVNOI DEYATELNOSTI IMENI I P PAVLOVA, 1973, 23 (03) : 651 - 652
  • [3] Effects of training of operant conditioned reflex on free amino acids in hippocampus of rats
    Shu, HJ
    Han, HW
    Zhao, R
    Chen, Y
    Liu, GQ
    CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE, 1999, 20 (11): : 1703 - 1707
  • [4] Acetylcholine release in the hippocampus during the operant conditioned reflex and the footshock stimulus in rats
    Dong, Y
    Mao, JJ
    Shangguan, DH
    Zhao, R
    Liu, GQ
    NEUROSCIENCE LETTERS, 2004, 369 (02) : 121 - 125
  • [5] Effects of Training of Operant Conditioned Reflex on Free Amino Acids in Hippocampus of Rats
    Shu, Hong-Jun
    Han, Hui-Wan
    Zhao, Rui
    Chen, Yi
    Liu, Guo-Quan
    Kao Teng Hsueh Hsiao Hua Heush Hsueh Pao/ Chemical Journal of Chinese Universities, 1999, 20 (11): : 1706 - 1707
  • [6] EFFECT OF HIPPOCAMPUS STIMULATION ON SPEED OF ACQUISITION A PROTECTIVE CONDITIONED REFLEX IN CATS
    GRALEWICZ, S
    ACTA PHYSIOLOGICA POLONICA, 1971, 22 (04): : 431 - +
  • [7] COMPARATIVE CONDITIONED PASSIVE-AVOIDANCE TEST STUDY OF THE EFFECT OF AMIRIDINE ON LEARNING AND MEMORY IN OLD RATS
    BUROV, YV
    ROBAKIDZE, TN
    VORONIN, AE
    BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 1992, 113 (01) : 60 - 63
  • [8] EFFECT OF HYPOKINESIA ON CONDITIONED-REFLEX ACTIVITY OF ALBINO RATS
    KHRULEVA, LN
    ENVIRONMENTAL SPACE SCIENCES-USSR, 1969, 3 (06): : 475 - &
  • [9] EFFECT OF HIPPOCAMPAL AND RETICULAR STIMULATION ON CONDITIONED REFLEX ACTIVITY IN RATS
    SZEKELY, JI
    BARGAR, I
    DENES, R
    KISS, I
    LITTMANN, J
    ACTA PHYSIOLOGICA ACADEMIAE SCIENTIARUM HUNGARICAE, 1968, 33 (04): : 395 - &
  • [10] Functional interactions of the suprachiasmatic nuclei and the hippocampus during the acquisition and recovery of a conditioned reflex to time in rats
    Vodolazhskaya M.G.
    Beier É.V.
    Popov A.V.
    Neuroscience and Behavioral Physiology, 2001, 31 (5) : 481 - 488
12345