Seroepidemiology of group C rotavirus infection in England and Wales

被引:33
|
作者
Iturriza-Gómara M. [1 ,5 ]
Clarke I. [2 ]
Desselberger U. [4 ]
Brown D. [1 ]
Thomas D. [3 ]
Gray J. [1 ]
机构
[1] Enteric Virus Unit, Enteric, Resp. Neurol. Virus Lab., Health Protection Agency, London
[2] Department of Molecular Microbiology, University Medical School, Southampton General Hospital, Southampton
[3] Communic. Dis. Survlnc. Centre Wales, Abton House, Cardiff, Wedal Road
[4] Virologie Molec. et Struct. UMR 2472, CNRS, Gif-sur-Yvette, Cedex
[5] Enteric Virus Unit, Enteric, Resp. Neurol. Virus Lab., Central Public Health Laboratory, London NW99 5HT, 61, Colindale Avenue
关键词
Group C rotavirus; Rural; Seroepidemiology; Urban;
D O I
10.1023/B:EJEP.0000032381.36658.cb
中图分类号
学科分类号
摘要
A total of 3199 serum samples collected in 1993-1994 from two population cohorts from England and Wales were tested for the prevalence of IgG antibodies specifically directed against group C rotavirus VP6. Seroprevalence was 39% (95% confidence intervals: 37.0-40.4%). Seroprevalence was highest (46.0%) in the oldest age group (61-70 years of age). Infection with group C rotaviruses occurred at an earlier age and with higher incidence in rural than in urban populations. These results may suggest transmission from animals to humans, however further work is required to identify the reservoir of group C rotavirus for human infection.
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页码:589 / 595
页数:6
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