Synthesis of novel tetra- and pentacyclic benzosultam scaffolds via domino Knoevenagel hetero-Diels–Alder reactions in water

被引：0

作者：

Mehdi Ghandi

Shahab Sheibani

Masoud Sadeghzadeh

Fariba Johari Daha

Maciej Kubicki

机构：

[1] University of Tehran,School of Chemistry, College of Science

[2] Radioisotope Research Group,Faculty of Chemistry

[3] NSTRI,undefined

[4] Adam Mickiewicz University in Poznan,undefined

来源：

Journal of the Iranian Chemical Society | 2013年 / 10卷

关键词：

Domino Knoevenagel hetero-Diels–Alder; Dihydropyrano[3,2-; ]chromen-5-ones; Dihydropyranopyrimidines; Benzosultams;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

An efficient catalyst-free and diastereoselective synthesis of novel dihydropyrano[2,3-d]pyrimidine and dihydropyrano[3,2-c]chromen-annulated benzosultams is described. A number of (E)-N-(2-formylphenyl)-N-methyl-2-phenylethenesulfonamides were synthesized and underwent a one-pot domino Knoevenagel hetero-Diels–Alder reaction, respectively, with N,N-dimethylbarbituric acid and 4-hydroxycoumarin in water, giving the desired products, in moderate to excellent yields.

引用

页码：1057 / 1065

页数：8

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