Synthesis and Anticonvulsive Activity of 5-Pyrrolidin-1-Ylpyrano[4″,3″:4′,5′]Pyrido-3′,2′:4,5]Thieno[3,2-D]Pyrimidine Derivatives

被引：0
|
作者：
Sh. Sh. Dashyan
E. G. Paronikyan
A. S. Noravyan
R. G. Paronikyan
机构：
[1] National Academy of Sciences of the Republic of Armenia,Institute of Fine Organic Chemistry, Science and Technology Center for Organic and Pharmaceutical Chemistry
来源：
Pharmaceutical Chemistry Journal | 2016年 / 50卷
关键词：
alkoxypyrido[2,3-; ]thieno[3,2-; ]pyrimidines; aminopyrido[2,3-; ]thieno[3,2-; ]pyrimidines; alkylsulfanylpyrido[2,3-; ]thieno[3,2-; ]pyrimidines; ethosuximide; anticonvulsive activity;
D O I：
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中图分类号：
学科分类号：
摘要：
A method for preparing the amino, alkoxy, and alkylsulfanyl derivatives of pyrano[4″,3″:4′,5′]pyrido-[3′,2′:4,5]thieno[3,2-d]pyrimidines based on 8-chloro-2,2-dimethyl-5-pyrrolidin-1-yl-1,4-dihydro-2H-pyrano[4″,3″:4′,5′]pyrido[3′,2′:4,5]thieno[3,2-d]pyrimidine was developed. The anticonvulsant activity of the compounds synthesized here was investigated.
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页码：221 / 225
页数：4
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