Genome-wide association study implicates novel loci and reveals candidate effector genes for longitudinal pediatric bone accrual

被引：0

作者：

Diana L. Cousminer

Yadav Wagley

James A. Pippin

Ahmed Elhakeem

Gregory P. Way

Matthew C. Pahl

Shana E. McCormack

Alessandra Chesi

Jonathan A. Mitchell

Joseph M. Kindler

Denis Baird

April Hartley

Laura Howe

Heidi J. Kalkwarf

Joan M. Lappe

Sumei Lu

Michelle E. Leonard

Matthew E. Johnson

Hakon Hakonarson

Vicente Gilsanz

John A. Shepherd

Sharon E. Oberfield

Casey S. Greene

Andrea Kelly

Deborah A. Lawlor

Benjamin F. Voight

Andrew D. Wells

Babette S. Zemel

Kurt D. Hankenson

Struan F. A. Grant

机构：

[1] Children’s Hospital of Philadelphia,Division of Human Genetics

[2] University of Pennsylvania,Department of Genetics

[3] Children’s Hospital of Philadelphia,Center for Spatial and Functional Genomics

[4] University of Michigan Medical School,Department of Orthopedic Surgery

[5] University of Bristol,MRC Integrative Epidemiology Unit, Population Health Science, Bristol Medical School

[6] University of Pennsylvania,Genomics and Computational Biology Graduate Group

[7] Imaging Platform,Division of Endocrinology and Diabetes

[8] Broad Institute of MIT and Harvard,Department of Pediatrics

[9] Children’s Hospital of Philadelphia,Department of Pediatrics

[10] Perelman School of Medicine,Division of Gastroenterology

[11] University of Pennsylvania,Department of Pediatrics, Cincinnati Children’s Hospital

[12] University of Pennsylvania Perelman School of Medicine,Department of Medicine and College of Nursing

[13] Hepatology and Nutrition,Division of Pulmonary Medicine

[14] Children’s Hospital of Philadelphia,Center for Endocrinology, Diabetes & Metabolism

[15] University of Cincinnati,Department of Epidemiology and Population Science

[16] Creighton University School of Medicine,Division of Pediatric Endocrinology

[17] Children’s Hospital of Philadelphia,Department of Systems Pharmacology and Translational Therapeutics

[18] Children’s Hospital Los Angeles,Institute of Translational Medicine and Therapeutics

[19] University of Hawaii Cancer Center,Department of Pathology and Laboratory Medicine

[20] Columbia University Medical Center,undefined

[21] University of Pennsylvania,undefined

[22] Childhood Cancer Data Lab,undefined

[23] Alex’s Lemonade Stand Foundation,undefined

[24] Perelman School of Medicine,undefined

[25] University of Pennsylvania,undefined

[26] University of Pennsylvania Perelman School of Medicine,undefined

来源：

Genome Biology | / 22卷

关键词：

Genome-wide association study; Osteoblasts; Osteogenesis; Gene mapping; Chromatin; CRISPR; Longitudinal analysis; Bone development; Skeletal development;

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[1] Genome-wide association study implicates novel loci and reveals candidate effector genes for longitudinal pediatric bone accrual
Cousminer, Diana L.
Wagley, Yadav
Pippin, James A.
Elhakeem, Ahmed
Way, Gregory P.
Pahl, Matthew C.
McCormack, Shana E.
Chesi, Alessandra
Mitchell, Jonathan A.
Kindler, Joseph M.
Baird, Denis
Hartley, April
Howe, Laura
Kalkwarf, Heidi J.
Lappe, Joan M.
Lu, Sumei
Leonard, Michelle E.
Johnson, Matthew E.
Hakonarson, Hakon
Gilsanz, Vicente
Shepherd, John A.
Oberfield, Sharon E.
Greene, Casey S.
Kelly, Andrea
Lawlor, Deborah A.
Voight, Benjamin F.
Wells, Andrew D.
Zemel, Babette S.
Hankenson, Kurt D.
Grant, Struan F. A.
[J]. GENOME BIOLOGY, 2021, 22 (01)
[2] Longitudinal genome-wide association study implicates novel loci and candidate genes for pediatric bone accrual
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Hankenson, Kurt
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McCormack, Shana
Chesi, Alessandra
Mitchell, Jonathan
Kindler, Joseph
Johnson, Matthew
Pippin, James
Hakonarson, Hakon
Zemel, Babette
Grant, Struan
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