Cerebrospinal fluid levels of transition metals in patients with Parkinson's disease

被引:0
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作者
F. J. Jiménez-Jiménez
J. A. Molina
M. V. Aguilar
I. Meseguer
C. J. Mateos-Vega
M. J. González-Muñoz
F. de Bustos
A. Martínez-Salio
M. Ortí-Pareja
M. Zurdo
M. C. Martínez-Para
机构
[1] Department of Neurology,
[2] Hospital Universitario "Príncipe de Asturias",undefined
[3] Alcalá de Henares,undefined
[4] ,undefined
[5] Department of Neurology and,undefined
[6] Department of Biochemistry,undefined
[7] Hospital Universitario Doce de Octubre,undefined
[8] and,undefined
[9] Department of Nutrition and Bromatology,undefined
[10] Faculty of Pharmacy,undefined
[11] University of Alcalá de Henares,undefined
[12] Madrid,undefined
[13] Spain,undefined
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Keywords: Parkinson's disease; transition metals; iron; copper; manganese; zinc; cerebrospinal fluid levels; serum levels.;
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摘要
We compared CSF and serum levels of iron, copper, manganese, and zinc, measured by atomic absorption spectrophotometry, in 37 patients with Parkinson's disease (PD) and 37 matched controls. The CSF levels of zinc were significantly decreased in PD patients as compared with controls (p < 0.05). The serum levels of zinc, and the CSF and serum levels of iron, copper, and manganese, did not differ significantly between PD-patient and control groups.
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页码:497 / 505
页数:8
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