Characterization of Missense Mutations in the SUP45 Gene of Saccharomyces cerevisiaeEncoding Translation Termination Factor eRF1*

被引：0
|
作者：
S. E. Moskalenko
G. A. Zhouravleva
M. Y. Soom
S. V. Chabelskaya
K. V. Volkov
O. M. Zemlyanko
M. Philippe
L. N. Mironova
S. G. Inge-Vechtomov
机构：
[1] St. Petersburg State University,Department of Genetics and Breeding
[2] University Rennes I,undefined
[3] UMR 6061,undefined
来源：
Russian Journal of Genetics | 2004年 / 40卷
关键词：
Saccharomyces Cerevisiae; Stop Codon; Missense Mutation; Amino Acid Substitution; Termination Factor;
D O I：
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中图分类号：
学科分类号：
摘要：
Collection of missense mutations in the SUP45 gene of Saccharomyces cerevisiae encoding translation termination factor eRF1 has been obtained by different approaches. It has been shown that most of isolated mutations cause amino acid substitutions in the N-terminal part of eRF1 and do not decrease the eRF1 amount. Most of mutations studied do not abolish eRF1–eRF3 interaction. The role of the N-terminal part of eRF1 in stop codon recognition is discussed.
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页码：478 / 484
页数：6
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