Synthesis and procoagulatory activity of n-(6-methyl-3-cyano-5-ethoxycarbonyl-2-pyridyl) aminoalkanecarboxylic acids

被引：0
|
作者：
M. E. Kon’shin
B. Ya. Syropyatov
M. I. Vakhrin
机构：
[1] Perm State Pharmaceutical Academy,
来源：
Pharmaceutical Chemistry Journal | 2009年 / 43卷
关键词：
Synthesis; N-(2-pyridyl)aminoalkanecarboxylic acid derivatives; hemostatic activity;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Interaction of 6-methyl-2-chloro-3-cyano-5-ethoxycarbonylpyridine with potassium salts of amino acids was shown to form N-(6-methyl-3-cyano-5-ethoxycarbonyl-2-pyridyl)aminoalkanecarboxylic acids. Most of the resulting substances had procoagulatory activity.
引用
收藏
页码：381 / 382
页数：1
相关论文
共 50 条
  • [1] Synthesis and procoagulatory activity of n-(6-methyl-3-cyano-5-ethoxycarbonyl-2-pyridyl) aminoalkanecarboxylic acids
    Kon'shin, M. E.
    Syropyatov, B. Ya.
    Vakhrin, M. I.
    PHARMACEUTICAL CHEMISTRY JOURNAL, 2009, 43 (07) : 381 - 382
  • [2] SYNTHESIS OF 3-CYANO-6-METHYL-4-PYRIDYL AND 3-CYANO-4-METHYL-6-PYRIDYL-PYRID-2(1H)-ONES
    HANFELD, V
    LEISTNER, S
    WAGNER, G
    PHARMAZIE, 1988, 43 (11): : 762 - 764
  • [3] SYNTHESIS OF 3-CYANO-4-ARYL-5-ETHOXYCARBONYL-6-METHYL-3,4-DIHYDROPYRIDINE-2-THIONES
    KRAUZE, AA
    LIEPINSH, EE
    PELCHER, JE
    KALME, ZA
    DIPAN, IV
    DUBUR, GJ
    KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 1985, (01): : 95 - 102
  • [4] Synthesis of 2-amino-4-aryl-3-cyano-6-methyl-5-ethoxycarbonyl-4H-pyrans
    Shestopalov, AM
    Niazimbetova, ZI
    Evans, DH
    Niyazymbetov, ME
    HETEROCYCLES, 1999, 51 (05) : 1101 - 1107
  • [5] Synthesis of 3-cyano-5-ethoxycarbonyl-6-hydroxypyridine-2-thiol derivatives
    Ya. Yu. Yakunin
    V. D. Dyachenko
    V. P. Litvinov
    Russian Chemical Bulletin, 1999, 48 : 195 - 196
  • [6] Synthesis of 3-cyano-5-ethoxycarbonyl-6-hydroxypyridine-2-thiol derivatives
    Yakunin, YY
    Dyachenko, VD
    Litvinov, VP
    RUSSIAN CHEMICAL BULLETIN, 1999, 48 (01) : 195 - 196
  • [7] N-(6-Methyl-2-pyridyl)formamide
    Hu, Hui-Ling
    Wu, Chia-Jun
    Cheng, Pei-Chi
    Chen, Jhy-Der
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2010, 66 : O180 - U2634
  • [8] Synthesis of 3-cyano-5-ethoxycarbonyl-4-methyl-6-phenylpyridine-2(1H)-thione and its alkylation
    Krivokolysko S.G.
    Dyachenko V.D.
    Litvinov V.P.
    Chemistry of Heterocyclic Compounds, 1999, 35 (12) : 1441 - 1442
  • [9] N-(4-Methylbenzyl)-N-(6-methyl-2-pyridyl)benzenesulfonamide
    Caylak, Nagihan
    Hoekelek, Tuncer
    Hasirci, Serdar
    Erguen, Yavuz
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2007, 63 : O2261 - O2262
  • [10] N-(3-Bromo-5-methyl-2-pyridyl)-4-methylbenzenesulfonamide
    Peng, Ming
    Luo, Youfu
    Chen, Lijuan
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2010, 66 : O205 - U2866
12345