Electrochemically reduced graphene oxide and gold nanoparticles on an indium tin oxide electrode  for voltammetric sensing of dopamine

被引：0
|
作者：
Xin Huang
Weishan Shi
Ning Bao
Chunmei Yu
Haiying Gu
机构：
[1] Nantong University,School of Public Health
来源：
Microchimica Acta | 2019年 / 186卷
关键词：
Surface electrochemical co-reduction; Disposable electrode; Differential pulse voltammetry; Electrochemical sensor; Cerebrospinal fluid;
D O I：
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学科分类号：
摘要：
The authors describe an electrochemical dopamine sensor that is based on the use of electrochemically co-reduced graphene oxide (Er-GO) and gold nanoparticles (AuNPs) on an indium-tin oxide (ITO) electrode. The synergistic effects of Er-GO and Er-AuNPs promote electron transport in the modified ITO. This results in an excellent performance for voltammetric sensing of dopamine (DA). Under the optimum conditions and a typical working potential of −0.05 V (vs. Ag/AgCl), the ITO electrode has a linear response in the 0.02–200 μM DA concentration range and a low detection limit of 15 nM. The sensor also showed a good selectivity over ascorbic acid and uric acid. The feasibility of the method was studied by analyzing DA in cerebrospinal fluid of rats.
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