Improved Tableting Properties of p-Hydroxybenzoic Acid by Water of Crystallization: A Molecular Insight

被引：0
|
作者：
Changquan (Calvin) Sun
David J. W. Grant
机构：
[1] University of Minnesota,Department of Pharmaceutics, College of Pharmacy
[2] Pharmacia Corporation,undefined
来源：
Pharmaceutical Research | 2004年 / 21卷
关键词：
hydrate; -hydroxybenzoic acid; plasticity; slip planes; tableting;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Purpose. To understand the influence of water in the crystal structure on the compaction properties of otherwise structurally similar crystals, p-hydroxybenzoic acid anhydrate (HA) and the monohydrate (HM) were used as model compounds.
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页码：382 / 386
页数：4
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