Candesartan Treatment for Peripheral Occlusive Arterial Disease after Stent AngioplastyA Randomised Placebo-Controlled Trial

被引：0
|
作者：
C. Schindler
J. Schweizer
A. Müller
R. Koch
G. Hellner
W. Fuchs
W. Kirch
机构：
[1] Medical Faculty of the University of Technology,Institute of Clinical Pharmacology
[2] Clinic for Internal Medicine 1,Department of Cardiology and Angiology
[3] Chemnitz Hospital,Institute for Medical Computer Science and Biometrics
[4] University of Technology,undefined
[5] Department of Clinical Research,undefined
[6] Takeda Pharma,undefined
来源：
Clinical Drug Investigation | 2005年 / 25卷
关键词：
Valsartan; Stent Implantation; Candesartan; Superficial Femoral Artery; Neointimal Hyperplasia;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Objectives: In this prospective, double-blind, placebo-controlled study we observed the influence of treatment with candesartan 8mg on restenosis rates after stent implantation into the femoral artery 6 months after percutaneous transluminal angioplasty (PTA). We hypothesised that angiotensin II type 1 (AT1)-receptor blockade with candesartan would reduce restenosis rates by reducing angiotensin II-mediated intima hyperproliferation within the stented vessel segment in patients with peripheral occlusive disease.
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页码：89 / 97
页数：8
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