The conundrum of B cell depletion in SLE

被引：0
|
作者：
Iñaki Sanz
机构：
[1] University of Rochester Medical Center,Division of Clinical Immunology & Rheumatology
来源：
Nature Reviews Rheumatology | 2009年 / 5卷
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摘要：
Two consecutive trials of rituximab, a B-cell-depleting anti-CD20 monoclonal antibody, have threatened the future of B-cell-targeted therapy for systemic lupus erythematosus (SLE). While rumors of the demise of this approach might be greatly exaggerated, the outcomes of these studies should force academics and the pharmaceutical industry back to the drawing board.
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页码：304 / 305
页数：1
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