PLACENTAL ENDOCRINE IGF2 DEFICIENCY IMPAIRS INTRAUTERINE GROWTH WITH CONSEQUENCES FOR INSULIN SENSITIVITY AND ADIPOSITY IN ADULT OFFSPRING

被引:0
|
作者
Yong, Hannah Ee Juen [1 ]
Lopez-Tello, Jorge [1 ]
Sandovici, Ionel [2 ,3 ,4 ]
Constancia, Miguel [2 ,3 ,4 ]
Sferruzzi-Perri, Amanda [1 ]
机构
[1] Univ Cambridge, Ctr Trophoblast Res, Cambridge, England
[2] Univ Cambridge, Wellcome Trust Med Res Council, Metab Res Labs, Inst Metab Sci, Cambridge, England
[3] Univ Cambridge, Wellcome Trust Med Res Council, MRC Metab Dis Unit, Inst Metab Sci, Cambridge, England
[4] Univ Cambridge, Dept Obstet & Gynaecol, Cambridge, England
关键词
D O I
暂无
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
P2.28
引用
收藏
页码:E60 / E61
页数:2
相关论文
共 14 条
  • [1] Placental IGF2 expression in normal and intrauterine growth restricted (IUGR) pregnancies
    Antonazzo, P.
    Alvino, G.
    Cozzi, V.
    Grati, F. R.
    Tabano, S.
    Sirchia, S.
    Miozzo, M.
    Cetin, I.
    PLACENTA, 2008, 29 (01) : 99 - 101
  • [2] Under-Expression of Placental Endocrine-Specific Igf2 Programmes Cardiovascular Disease in the Adult Male Offspring.
    Ching, W.
    Niu, Y.
    Garrud, T. A.
    Yong, H.
    Christoforou, E. R.
    Lopez-Tello, J.
    Giussani, D. A.
    Sferruzzi-Perri, A. N.
    REPRODUCTIVE SCIENCES, 2020, 27 (SUPPL 1) : 69A - 70A
  • [3] Under-Expression of Placental Endocrine-Specific Igf2 Programmes Cardiovascular Disease in the Adult Male Offspring.
    Ching, W.
    Niu, Y.
    Garrud, T. A.
    Yong, H.
    Christoforou, E. R.
    Lopez-Tello, J.
    Giussani, D. A.
    Sferruzzi-Perri, A. N.
    REPRODUCTIVE SCIENCES, 2021, 28 (SUPPL 1) : 86A - 86A
  • [4] Placental expression of PHLDA2 and IGF2 in selective intrauterine growth restriction in monozygotic twins
    Chen, Jie
    Pan, Shilei
    Hang, Lilin
    Zhong, Mei
    Yu, Yanhong
    INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY, 2018, 11 (02): : 876 - 881
  • [5] Gestational low dietary protein induces intrauterine inflammation and alters the programming of adiposity and insulin sensitivity in the adult offspring
    Mohammed, Shujauddin
    Qadri, Syed Shah Yousuf Hussain
    Molangiri, Archana
    Basak, Sanjay
    Rajkumar, Hemalatha
    JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2023, 116
  • [6] The visceral adiposity index is associated with insulin sensitivity and IGF-I levels in adults with growth hormone deficiency
    Alessandro Ciresi
    Stefano Radellini
    Valentina Guarnotta
    Carla Giordano
    Endocrine, 2017, 56 : 579 - 588
  • [7] The visceral adiposity index is associated with insulin sensitivity and IGF-I levels in adults with growth hormone deficiency
    Ciresi, Alessandro
    Radellini, Stefano
    Guarnotta, Valentina
    Giordano, Carla
    ENDOCRINE, 2017, 56 (03) : 579 - 588
  • [8] Placental Endocrine Function and Insulin-Like Growth Factor-2 (Igf2) Are Important Determinants of Maternal Metabolic State and Fetal Growth in Obese Mouse Pregnancies.
    Lean, Samantha C.
    Petres, Esteban Salazar
    Gulacsi, Edina
    Sferruzzi-Perri, Amanda N.
    REPRODUCTIVE SCIENCES, 2021, 28 (SUPPL 1) : 262A - 262A
  • [9] Early exercise regimen improves insulin sensitivity in the intrauterine growth-restricted adult female rat offspring
    Garg, Meena
    Thamotharan, Manikkavasagar
    Oak, Shilpa A.
    Pan, Gerald
    MacLaren, Duncan C.
    Lee, Paul W. N.
    Devaskar, Sherin U.
    AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2009, 296 (02): : E272 - E281
  • [10] Decreased Placental Methylation at the H19/IGF2 Imprinting Control Region is Associated with Normotensive Intrauterine Growth Restriction but not Preeclampsia
    Bourque, D. K.
    Avila, L.
    Penaherrera, M.
    von Dadelszen, P.
    Robinson, W. P.
    PLACENTA, 2010, 31 (03) : 197 - 202