Cell Polarity: A Link to Epithelial-Mesenchymal Transition and Vascular Mimicry

被引：5
|
作者：
Bhattacharya, Susinjan [1 ]
机构：
[1] JIIT, Dept Biotechnol, A-10,Sect 62, Noida 7, UP, India
来源：
CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION | 2018年 / 28卷 / 02期
关键词：
cell polarity; par complexes; epithelial-mesenchymal transition; vascular mimicry; COMPLEX; CANCER; PROGRESSION; ACTIVATION; MECHANISMS; PROTEINS;
D O I：
10.1615/CritRevEukaryotGeneExpr.2018020775
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Cell polarity is an essential process for development, cell physiology and tissue homeostasis. Loss of cell polarity is a characteristic feature of cancer. This review highlights the factors involved in maintenance of cell polarity and looks at the link between cell polarity, epithelial mesenchymal transition (EMT) and cancer and finally tries to draw link between cell polarity and vascular mimicry in EMT occurring cells.
引用
收藏
页码：101 / 105
页数：5
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