The oncogenic potential of the homeobox gene Cdx2 is depending on the MAPK pathway and can be antagonized by the MEK1/2 inhibitor PD98059 in a mouse model of t(12;13)(p13;q12) positive AML.

被引：0
|
作者：
Rawat, VPS
Naidu, VM
Schessl, C
Cusan, M
Humphries, RK
Lynch, JP
Hiddemann, W
Feuring-Buske, M
Buske, C
机构：
[1] Klinikum Grosshadern, Clin Cooperat Grp Leukemia, Natl Res Ctr Environm & Hlth, GSF, Munich, Germany
[2] Klinikum Grosshadern, Dept Med 111, Munich, Germany
[3] BC Canc Agcy, Terry Fox Lab, Vancouver, BC, Canada
[4] Univ Penn, Div Gastroenterol, Dept Med, Philadelphia, PA 19104 USA
来源：
BLOOD | 2004年 / 104卷 / 11期
关键词：
D O I：
10.1182/blood.V104.11.1975.1975
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
1975
引用
收藏
页码：545A / 545A
页数：1
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