Astatine-211 imaging by a Compton camera for targeted radiotherapy

被引：17

作者：

Nagao, Yuto ^{[1
,2
]}

Yamaguchi, Mitsutaka ^{[1
]}

Watanabe, Shigeki ^{[1
]}

Ishioka, Noriko S. ^{[1
]}

Kawachi, Naoki ^{[1
]}

Watabe, Hiroshi ^{[1
,2
,3
]}

机构：

[1] Natl Inst Quantum & Radiol Sci & Technol, Takasaki Adv Radiat Res Inst, 1233 Watanuki, Takasaki, Gunma 3701292, Japan

[2] Tohoku Univ, Grad Sch Biomed Engn, Aoba Ku, 6-6-12 Aoba, Sendai, Miyagi 9808579, Japan

[3] Tohoku Univ, Cyclotron & Radioisotope Ctr, Aoba Ku, 6-3 Aoba, Sendai, Miyagi 9808578, Japan

来源：

APPLIED RADIATION AND ISOTOPES | 2018年 / 139卷

关键词：

Astatine-211; Compton camera; Monte Carlo simulation; Targeted radiotherapy; NEUTRON-CAPTURE THERAPY; NUCLEAR-DATA SHEETS; PROMPT GAMMA-RAYS; AT-211; DOSIMETRY; SYSTEM;

D O I：

10.1016/j.apradiso.2018.05.022

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Astatine-211 is a promising radionuclide for targeted radiotherapy. It is required to image the distribution of targeted radiotherapeutic agents in a patient's body for optimization of treatment strategies. We proposed to image At-211 with high-energy photons to overcome some problems in conventional planar or single-photon emission computed tomography imaging. We performed an imaging experiment of a point-like At-211 source using a Compton camera, and demonstrated the capability of imaging At-211 with the high-energy photons for the first time.

引用

页码：238 / 243

页数：6

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