Outcomes of patients with IDH1-mutant relapsed or refractory acute myeloid leukemia receiving ivosidenib who proceeded to hematopoietic stem cell transplant

被引:10
|
作者
DiNardo, Courtney D. [1 ]
Stein, Eytan M. [2 ]
Pigneux, Arnaud [3 ]
Altman, Jessica K. [4 ]
Collins, Robert [5 ]
Erba, Harry P. [6 ]
Watts, Justin M. [7 ]
Uy, Geoffrey L. [8 ]
Winkler, Thomas [9 ]
Wang, Hongfang [9 ]
Choe, Sung [9 ]
Liu, Hua [9 ]
Wu, Bin [9 ]
Kapsalis, Stephanie M. [9 ]
Roboz, Gail J. [10 ,11 ]
de Botton, Stephane [12 ]
机构
[1] Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA
[2] Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA
[3] CHU Bordeaux, Bordeaux, France
[4] Northwestern Univ, Chicago, IL 60611 USA
[5] Univ Texas Southwestern Med Ctr Dallas, Dallas, TX 75390 USA
[6] Univ Alabama Birmingham, Birmingham, AL USA
[7] Univ Miami, Sylvester Comprehens Canc Ctr, Miami, FL USA
[8] Washington Univ, Sch Med, St Louis, MO 63110 USA
[9] Agios Pharmaceut Inc, Cambridge, MA USA
[10] Weill Cornell Med, New York, NY USA
[11] New York Presbyterian Hosp, New York, NY USA
[12] Inst Gustave Roussy, Villejuif, France
关键词
AML;
D O I
10.1038/s41375-021-01229-x
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
[No abstract available]
引用
收藏
页码:3278 / 3281
页数:4
相关论文
共 50 条
  • [1] Outcomes of patients with IDH1-mutant relapsed or refractory acute myeloid leukemia receiving ivosidenib who proceeded to hematopoietic stem cell transplant
    Courtney D. DiNardo
    Eytan M. Stein
    Arnaud Pigneux
    Jessica K. Altman
    Robert Collins
    Harry P. Erba
    Justin M. Watts
    Geoffrey L. Uy
    Thomas Winkler
    Hongfang Wang
    Sung Choe
    Hua Liu
    Bin Wu
    Stephanie M. Kapsalis
    Gail J. Roboz
    Stéphane de Botton
    Leukemia, 2021, 35 : 3278 - 3281
  • [2] Ivosidenib (IVO) prior to hematopoietic cell transplant for patients with IDH1-mutant relapsed or refractory acute myeloid leukemia (R/R AML).
    Dinardo, Courtney Denton
    Stein, Eytan
    Pigneux, Arnaud
    Altman, Jessica K.
    Collins, Robert
    Erba, Harry Paul
    Watts, Justin M.
    Uy, Geoffrey L.
    Kapsalis, Stephanie M.
    Liu, Hua
    Winkler, Thomas
    Roboz, Gail J.
    de Botton, Stephane
    JOURNAL OF CLINICAL ONCOLOGY, 2020, 38 (15)
  • [3] EXPOSURE-RESPONSE ANALYSIS OF IVOSIDENIB IN PATIENTS WITH IDH1-MUTANT RELAPSED OR REFRACTORY ACUTE MYELOID LEUKEMIA.
    Le, K.
    Kleijn, H. J.
    Dai, D.
    Fan, B.
    Liu, H.
    Attar, E. C.
    Hickman, D.
    Agresta, S. V.
    Yang, H.
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 2019, 105 : S85 - S85
  • [4] Ivosidenib (IVO) Prior to Hematopoietic Cell Transplant (HCT) for Patients with IDH1-Mutant Relapsed or Refractory Acute Myeloid Leukemia (R/R AML) Who Cannot Tolerate Intensive Chemotherapy (IC)
    DiNardo, Courtney D.
    Stein, Eytan M.
    Pigneux, Arnaud
    Altman, Jessica K.
    Collins, Robert
    Erba, Harry P.
    Watts, Justin M.
    Uy, Geoffrey L.
    Wu, Bin
    Choe, Sung
    Kapsalis, Stephanie M.
    Liu, Hua
    Winkler, Thomas
    Roboz, Gail J.
    de Botton, Stephane
    CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2020, 20 : S197 - S198
  • [5] Molecular Mechanisms Mediating Relapse Following Ivosidenib Monotherapy in Patients with IDH1-Mutant Relapsed or Refractory Acute Myeloid Leukemia
    Choe, Sung
    Wang, Hongfang
    DiNardo, Courtney D.
    Stein, Eytan M.
    De Botton, Stephane
    Fathi, Amir T.
    Tallman, Martin S.
    Kantarjian, Hagop M.
    Stone, Richard M.
    Quek, Lynn
    Konteatis, Zenon
    Dang, Lenny
    Zhang, Vickie
    Liu, Hua
    Attar, Eyal C.
    Wu, Bin
    BLOOD, 2019, 134
  • [6] Complex Polyclonal Resistance Mechanisms to Ivosidenib Monotherapy in IDH1-Mutant Relapsed or Refractory Acute Myeloid Leukemia Revealed By Single Cell Sequencing Analyses
    Wang, Hongfang
    Choe, Sung
    DiNardo, Courtney D.
    Stein, Eytan M.
    de Botton, Stephane
    Fathi, Amir T.
    Tallman, Martin S.
    Kantarjian, Hagop M.
    Stone, Richard M.
    Quek, Lynn
    Zhang, Vickie
    Liu, Hua
    Attar, Eyal C.
    Wu, Bin
    BLOOD, 2019, 134
  • [7] Ivosidenib induces deep durable remissions in patients with newly diagnosed IDH1-mutant acute myeloid leukemia
    Roboz, Gail J.
    DiNardo, Courtney D.
    Stein, Eytan M.
    de Botton, Stephane
    Mims, Alice S.
    Prince, Gabrielle T.
    Altman, Jessica K.
    Arellano, Martha L.
    Donnellan, Will
    Erba, Harry P.
    Mannis, Gabriel N.
    Pollyea, Daniel A.
    Stein, Anthony S.
    Uy, Geoffrey L.
    Watts, Justin M.
    Fathi, Amir T.
    Kantarjian, Hagop M.
    Tallman, Martin S.
    Choe, Sung
    Dai, David
    Fan, Bin
    Wang, Hongfang
    Zhang, Vickie
    Yen, Katharine E.
    Kapsalis, Stephanie M.
    Hickman, Denice
    Liu, Hua
    Agresta, Samuel, V
    Wu, Bin
    Attar, Eyal C.
    Stone, Richard M.
    BLOOD, 2020, 135 (07) : 463 - 471
  • [8] Longitudinal Molecular Profiling in Patients with IDH1-Mutant Newly Diagnosed Acute Myeloid Leukemia Treated with Ivosidenib
    Choe, Sung
    Wang, Hongfang
    Roboz, Gail J.
    DiNardo, Courtney D.
    Stein, Eytan M.
    Mims, Alice S.
    Prince, Gabrielle T.
    Watts, Justin M.
    Fan, Bin
    Nejad, Parham
    Zhang, Vickie
    Liu, Hua
    Attar, Eyal C.
    Wu, Bin
    Stone, Richard M.
    BLOOD, 2020, 136
  • [9] Ivosidenib for the treatment of relapsed or refractory acute myeloid leukemia with an IDH1 mutation
    Pasquier, Florence
    Chahine, Claude
    Marzac, Christophe
    de Botton, Stephane
    EXPERT REVIEW OF PRECISION MEDICINE AND DRUG DEVELOPMENT, 2020, 5 (06): : 429 - 438
  • [10] Ivosidenib (AG-120) in Mutant IDH1 Relapsed/Refractory Acute Myeloid Leukemia: Results of a Phase 1 Study
    DiNardo, Courtney D.
    Stein, Eytan M.
    de Botton, Stephane
    Roboz, Gail J.
    Altman, Jessica K.
    Mims, Alice S.
    Swords, Ronan
    Collins, Robert H.
    Mannis, Gabriel N.
    Pollyea, Daniel A.
    Donnellan, Will
    Fathi, Amir T.
    Pigneux, Arnaud
    Erba, Harry P.
    Prince, Gabrielle T.
    Stein, Anthony S.
    Uy, Geoffrey L.
    Foran, James M.
    Traer, Elie
    Stuart, Robert K.
    Arellano, Martha L.
    Slack, James L.
    Sekeres, Mikkael A.
    Willekens, Christophe
    Choe, Sung
    Wang, Hongfang
    Zhang, Vickie
    Yen, Katharine E.
    Kapsalis, Stephanie M.
    Yang, Hua
    Dai, David
    Fan, Bin
    Goldwasser, Meredith
    Liu, Hua
    Agresta, Sam
    Wu, Bin
    Attar, Eyal C.
    Tallman, Martin S.
    Stone, Richard M.
    Kantarjian, Hagop M.
    CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2018, 18 : S204 - S205