Optic neuropathy in refractory neurosarcoidosis treated with TNF-α antagonist

被引：28
|
作者：
Salama, Batoul
Gicquel, Jean-Jacques
Lenoble, Patrice
Dighiero, Paul Louis
机构：
[1] Hop Jean Bernard, Dept Ophthalmol, F-86021 Poitiers, France
[2] Univ Poitiers Hosp, Federat Inter Hosp Picto Charentaise Ophthalmol, Poitiers, France
[3] Univ Poitiers Hosp, Dept Ophthalmol, Poitiers, France
[4] Univ Poitiers Hosp, Mulhouses Gen Hosp, Dept Ophthalmol, Poitiers, France
来源：
CANADIAN JOURNAL OF OPHTHALMOLOGY-JOURNAL CANADIEN D OPHTALMOLOGIE | 2006年 / 41卷 / 06期
关键词：
refractory neurosarcoidosis; optic neuropathy; infliximab;
D O I：
10.1139/I06-074
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
Case report: To report a rare case of optic neuropathy in refractory neurosarcoidosis treated with tumour necrosis factor-cc antagonist (infliximab) perfusion. A 41-year-old man with diabetes presented with an abrupt, painless, unilateral visual loss. Thoracic computed tomography disclosed mediastinal lymphadenopathy, and evidence from histopathology confirmed sarcoidosis. Comments: Corticosteroids alone and with immunosuppressive agents failed to suppress the active disease. Alternative therapy of infliximab perfusions resulted in disease remission and relative visual improvement, and this treatment may warrant further clinical studies.
引用
收藏
页码：766 / 768
页数：3
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