Enterovirus D68 and other enterovirus serotypes identified in South African patients with severe acute respiratory illness, 2009-2011

被引:9
|
作者
Hellferscee, Orienka [1 ,2 ]
Treurnicht, Florette K. [1 ]
Tempia, Stefano [1 ,3 ]
Variava, Ebrahim [2 ,4 ]
Dawood, Halima [4 ,5 ]
Kahn, Kathleen [2 ]
Cohen, Adam L. [3 ]
Pretorius, Marthi [6 ]
Cohen, Cheryl [1 ,2 ]
Madhi, Shabir A. [1 ,2 ]
Venter, Marietjie [3 ,6 ]
机构
[1] Natl Inst Communicable Dis, Natl Hlth Lab Serv, Johannesburg, South Africa
[2] Univ Witwatersrand, Johannesburg, South Africa
[3] Ctr Dis Control & Prevent, Atlanta, GA USA
[4] Pietermaritzburg Metropolitan Hosp, Pietermaritzburg, South Africa
[5] Univ KwaZulu Natal, Caprisa, Pietermaritzburg, South Africa
[6] Univ Pretoria, Pretoria, South Africa
关键词
enterovirus; EV-D68; pneumonia; South Africa; INFECTIONS; PREVALENCE; EMERGENCE; INFLUENZA; CHILDREN; GERMANY;
D O I
10.1111/irv.12444
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
BackgroundHuman enteroviruses (EV) have been associated with severe acute respiratory illness (SARI) in South Africa. ObjectivesWe aimed to describe the molecular epidemiology of EV serotypes among patients hospitalized with SARI during 2009-2011. Patients/MethodsStudy samples from patients were tested for the presence of enterovirus using a polymerase chain reaction assay. Results8.2% (842/10260) of SARI cases tested positive for enterovirus; 16% (7/45) were species EV-A, 44% (20/45) EV-B, 18% (8/45) EV-C and 22% (10/45) EV-D. Seventeen different EV serotypes were identified within EV-A to EV-D, of which EV-D68 (22%; 10/45) and Echovirus 3 (11%; 5/45) were the most prevalent. ConclusionsEV-D68 should be monitored in South Africa to assess the emergence of highly pathogenic strains.
引用
收藏
页码:211 / 219
页数:9
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