Nonalcoholic Fatty Liver Disease after Liver Transplant

被引:14
|
作者
Shetty, Akshay [1 ]
Giron, Fanny [2 ]
Divatia, Mukul K. [3 ]
Ahmad, Muhammad, I [1 ]
Kodali, Sudha [1 ]
Victor, David [1 ]
机构
[1] Houston Methodist Hosp, Sherrie & Alan Conover Ctr Liver Dis & Transplant, Dept Med, Outpatient Ctr 22nd Floor, Houston, TX 77030 USA
[2] Houston Methodist Hosp, Dept Med, Houston, TX 77030 USA
[3] Houston Methodist Hosp, Weill Cornell Med Coll, Dept Pathol & Genom Med, Houston, TX 77030 USA
关键词
Nonalcoholic fatty liver disease; Nonalcoholic steatohepatitis; Post-transplant; Recurrent NAFLD; De novo NAFLD; Recurrent NASH; De novo NASH; CRYPTOGENIC CIRRHOSIS; AMERICAN ASSOCIATION; BARIATRIC SURGERY; NATURAL-HISTORY; SCORING SYSTEM; STEATOHEPATITIS; PREVALENCE; RECIPIENTS; RECURRENCE; EPIDEMIOLOGY;
D O I
10.14218/JCTH.2020.00072
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Nonalcoholic fatty liver disease (NAFLD) is one of the most common causes of chronic liver disease in the world. The rising prevalence of nonalcoholic steatohepatitis (NASH) has led to a 170% increase in NASH cirrhosis as the listing indication for liver transplantation from 2004 to 2013. As of 2018, NASH has overtaken hepatitis C as an indication for liver transplantation in the USA. After liver transplantation, the allograft often develops recurrent NAFLD among patients with known NASH cirrhosis. In addition to recurrent disease, de novo NAFLD has been reported in patients with other indications for liver transplantation. In this review, we will discuss the risk factors associated with recurrent and de novo NAFLD, natural course of the disease, and management strategies after liver transplantation.
引用
收藏
页码:428 / 435
页数:8
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