Molecular Profiling in Cutaneous Melanoma

被引：4
|
作者：
Ji, Andrew L. [1 ,2 ,3 ]
Bichakjian, Christopher K. [4 ]
Swetter, Susan M. [1 ,2 ,3 ]
机构：
[1] VA Palo Alto Hlth Care Syst, Dermatol Serv, Palo Alto, CA USA
[2] Stanford Univ, Med Ctr, Stanford, CA 94305 USA
[3] Inst Canc Res, Dept Dermatol, Pigmented Les & Melanoma Program, Stanford, CA USA
[4] Univ Michigan Hlth Syst, Dept Dermatol, Ann Arbor, MI USA
来源：
JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK | 2016年 / 14卷 / 04期
关键词：
LYMPH-NODE BIOPSY; PHASE-III TRIAL; GENE-EXPRESSION; HIGH-RISK; SIGNATURE; CANCER; ASSAY; FISH; INTERFERON-ALPHA-2B; VALIDATION;
D O I：
10.6004/jnccn.2016.0052
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Molecular profiling of malignant tumors is gaining increasing interest in oncology. In recent years, several molecular techniques have been studied in melanoma, with the goal to improve upon the diagnostic and prognostic abilities of currently available clinical and histopathologic parameters. Reliable tests performed early in the diagnosis and management of melanoma could lead to decreased morbidity and mortality by selecting appropriate patients for more-aggressive therapy and sparing those for whom it is not indicated. This article reviews the molecular diagnostic and prognostic techniques currently available for melanoma and evaluates their potential role in clinical practice.
引用
收藏
页码：475 / 480
页数：6
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