A smoking cessation trial with lobeline sulfate: A pilot study

被引：0

作者：

Glover, ED

Leischow, SJ

Rennard, SI

Glover, PN

Daughton, D

Quiring, JN

Schneider, FH

Mione, PJ

机构：

[1] W Virginia Univ, Sch Med, MBRCC, Tobacco Res Ctr,Robert C Byrd Hlth Sci Ctr, Morgantown, WV 26506 USA

[2] Univ Arizona, Dept Family Med, Tucson, AZ USA

[3] Univ Arizona, Arizona Program Nicotine & Tobacco Res, Tucson, AZ USA

[4] Univ Nebraska, Med Ctr, Dept Internal Med Pulm & Clin Care Med, Omaha, NE USA

[5] QST Consultants Ltd, Allendale, MI USA

[6] DynaGen Inc, Cambridge, MA USA

来源：

AMERICAN JOURNAL OF HEALTH BEHAVIOR | 1998年 / 22卷 / 01期

关键词：

D O I：

暂无

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Objective: To evaluate a sublingual formulation of lobeline sulfate for smoking cessation. Methods: Random assignment of 180 healthy smokers to treatment (n=90) or placebo (n=90). Treatment was self-administering a 7.5 mg lobeline sulfate sublingual or placebo tablet 9 times per day for 6 weeks. Results: No difference in cessation efficacy between placebo and active treatment. Among highly dependent smokers who completed the trial, there was a trend for higher cessation rates in the active group. Conclusion: This pilot study failed to demonstrate smoking-cessation efficacy. However, data suggest continued studies to evaluate lobeline sulfate for smoking cessation.

引用

页码：62 / 74

页数：13

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