Practical considerations for the use of direct oral anticoagulants in oncology patients

被引：1
|
作者：
Duong, Arianne [1 ,2 ]
Sing, Sarah [1 ,2 ]
Taketa, Cathy [1 ,2 ]
Miske, Abby [1 ,2 ]
Segal, Eve [1 ,2 ]
Garcia, David [3 ]
机构：
[1] Univ Washington, Dept Pharm, Seattle, WA 98195 USA
[2] Seattle Canc Care Alliance, Dept Pharm, Seattle, WA USA
[3] Univ Washington, Sch Med, Dept Hematol, Seattle, WA USA
来源：
JOURNAL OF ONCOLOGY PHARMACY PRACTICE | 2020年 / 26卷 / 03期
关键词：
Anticoagulation; cancer-associated VTE; DOAC; hemorrhage; venous thromboembolism; MOLECULAR-WEIGHT-HEPARIN; VENOUS THROMBOEMBOLISM; INTRACRANIAL HEMORRHAGE; ATRIAL-FIBRILLATION; ANDEXANET ALPHA; BODY-WEIGHT; CANCER; MANAGEMENT; PHARMACOKINETICS; PHARMACODYNAMICS;
D O I：
10.1177/1078155219893008
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Oncology patients are at a high risk of experiencing venous thromboembolism. Historically, venous thromboembolisms in cancer patients have been managed with low-molecular-weight heparin on the basis of the CLOT trial published in 2003. However, recent prospective data provide evidence for safe and effective direct oral anticoagulant use in this population. The purpose of this review article is to evaluate the current body of literature surrounding direct oral anticoagulant use in the oncology population and to highlight key practical considerations when prescribing these agents for patients with cancer.
引用
收藏
页码：692 / 702
页数：11
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