In this study we performed a retrospective chart review to evaluate the efficacy of short-term postoperative oral amiodarone therapy on postoperative atrial fibrillation (POAF) after coronary artery bypass surgery. The incidence of POAF in 372 patients (60.6%) without prophylactic amiodarone therapy was compared with that in 240 patients (39.4%) receiving the medication immediately after the surgery. Patients who received prophylactic amiodarone developed significantly less POAF than those without prophylactic treatment (17.0% versus 25.9%, P = .01), with relative and absolute risk reductions of 0.7% and 8.9%, respectively. Postoperative oral amiodarone therapy is simple to administer and may be a valuable adjunct therapy for patients after coronary artery bypass surgery.
机构:
Dept Adm President Russian Federat, FSBI Cent Clin Hosp Polyclin, Moscow, RussiaDept Adm President Russian Federat, FSBI Cent Clin Hosp Polyclin, Moscow, Russia
Petrakova, E. S.
Savina, N. M.
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Dept Adm President Russian Federat, FSBI DPO Cent State Med Acad, Moscow, RussiaDept Adm President Russian Federat, FSBI Cent Clin Hosp Polyclin, Moscow, Russia
Savina, N. M.
Molochkov, A., V
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Dept Adm President Russian Federat, FSBI Cent Clin Hosp Polyclin, Moscow, RussiaDept Adm President Russian Federat, FSBI Cent Clin Hosp Polyclin, Moscow, Russia
机构:
King Hussein Med Ctr, Royal Med Serv, QAHI, Dept Cardiac Surg, Prince Hamzed Suburb 11733, JordanKing Hussein Med Ctr, Royal Med Serv, QAHI, Dept Cardiac Surg, Prince Hamzed Suburb 11733, Jordan
Harahsheh, BS
Sawalha, WA
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King Hussein Med Ctr, Royal Med Serv, QAHI, Dept Cardiac Surg, Prince Hamzed Suburb 11733, JordanKing Hussein Med Ctr, Royal Med Serv, QAHI, Dept Cardiac Surg, Prince Hamzed Suburb 11733, Jordan