Association between smoking and environmental tobacco smoke with lung cancer risk: a case-control study in the Fujian Chinese population

被引:3
|
作者
Zhuang, Jinman [1 ,2 ,3 ]
Liu, Zhi Qiang [1 ,2 ,3 ]
Xiao, Rendong [4 ]
Xu, Qiu Ping [5 ]
Xiong, Wei Min [1 ,2 ,3 ]
Li, Xu [4 ]
Cai, Lin [1 ,2 ,3 ]
He, Fei [1 ,2 ,3 ]
机构
[1] Fujian Med Univ, Sch Publ Hlth, Dept Epidemiol, Fuzhou, Peoples R China
[2] Fujian Med Univ, Sch Publ Hlth, Fujian Prov Key Lab Environm Factors & Canc, Fuzhou, Peoples R China
[3] Fujian Med Univ, Key Lab, Minist Educ Gastrointestinal Canc, Fuzhou, Peoples R China
[4] Fujian Med Univ, Affiliated Hosp 1, Dept Thorac Surg, Fuzhou, Peoples R China
[5] Putian Univ, Affifiliated Hosp, Med Dept, Putian, Peoples R China
来源
JOURNAL OF PUBLIC HEALTH-HEIDELBERG | 2022年 / 30卷 / 08期
基金
中国国家自然科学基金;
关键词
Smoking; Environmental tobacco smoke; Lung cancer; Case– control studies; PASSIVE SMOKING; NEVER SMOKERS; EXPOSURE; CIGARETTES; TRENDS; RATES; COAL;
D O I
10.1007/s10389-021-01573-3
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Aim To investigate the association between smoking, environmental tobacco smoke (ETS), and lung cancer risk. Methods This case-control study included 1622 newly diagnosed cases of lung cancer and 1622 healthy frequency-, age-, and gender-matched control participants. Epidemiological data were collected by in-person interviews using a standard questionnaire. Results Smoking was a risk factor for lung cancer in men (odds ratio (OR) = 4.486, 95% confidence interval (95%CI) 3.586-5.611). In addition, decreased starting age, increased number of cigarettes smoked per day, duration of smoking, pack-years, and depth of inhalation were all risk factors that met the dose-response relationship (P < 0.001). The risk of lung cancer was lower among men who had quit smoking for more than 10 years compared to current smokers. Additionally, male smokers with lung squamous cell carcinoma were at a higher risk of lung cancer than male smokers with lung adenocarcinoma. Workplace ETS increased the risk for lung cancer for male nonsmokers (OR = 2.452, 95%CI 1.534-3.920). In contrast, household ETS increased the risk for lung cancer for female nonsmokers (OR = 2.224, 95%CI 1.644-3.009). Approximately 65.93% cases of lung cancer in men could be attributed to smoking, whereas approximately 31.03% cases of lung cancer among nonsmokers could be attributed to ETS. Conclusions Smoking is the main risk factor for lung cancer. Workplace ETS is associated with increased lung cancer risk in male nonsmokers, while household ETS is associated with increased lung cancer risk in nonsmoking women. Thus, smoking and ETS increase the risk of lung cancer and are major public health concerns.
引用
收藏
页码:2047 / 2057
页数:11
相关论文
共 50 条
  • [1] Association between smoking and environmental tobacco smoke with lung cancer risk: a case–control study in the Fujian Chinese population
    Jinman Zhuang
    Zhi qiang Liu
    Rendong Xiao
    Qiu ping Xu
    Wei min Xiong
    Xu Li
    Lin Cai
    Fei He
    [J]. Journal of Public Health, 2022, 30 : 2047 - 2057
  • [2] Smoking, environmental tobacco smoke, and risk of renal cell cancer: a population-based case-control study
    Theis, Ryan P.
    Grieb, Suzanne M. Dolwick
    Burr, Deborah
    Siddiqui, Tariq
    Asal, Nabih R.
    [J]. BMC CANCER, 2008, 8 (1)
  • [3] Smoking, environmental tobacco smoke, and risk of renal cell cancer: a population-based case-control study
    Ryan P Theis
    Suzanne M Dolwick Grieb
    Deborah Burr
    Tariq Siddiqui
    Nabih R Asal
    [J]. BMC Cancer, 8
  • [4] Environmental tobacco smoke and lung cancer:: A case-control study in Germany
    Kreuzer, M
    Krauss, M
    Kreienbrock, L
    Jöckel, KH
    Wichmann, HE
    [J]. AMERICAN JOURNAL OF EPIDEMIOLOGY, 2000, 151 (03) : 241 - 250
  • [5] Exposure to environmental tobacco smoke (ETS) and risk of lung cancer in Montreal: a case-control study
    Al-Zoughool, Mustafa
    Pintos, Javier
    Richardson, Lesley
    Parent, Marie-Elise
    Ghadirian, Parviz
    Krewski, Daniel
    Siemiatycki, Jack
    [J]. ENVIRONMENTAL HEALTH, 2013, 12
  • [6] Smoking, Environmental Tobacco Smoke, and Risk of Renal Cell Cancer: A Population-Based Case-Control Study Editorial Comment
    Marshall, Fray F.
    [J]. JOURNAL OF UROLOGY, 2009, 182 (05): : 2204 - 2204
  • [7] Multicenter case-control study of exposure to environmental tobacco smoke and lung cancer in Europe
    Boffetta, P
    Agudo, A
    Ahrens, W
    Benhamou, E
    Benhamou, S
    Darby, SC
    Ferro, G
    Fortes, C
    Gonzalez, CA
    Jöckel, KH
    Krauss, M
    Kreienbrock, L
    Kreuzer, M
    Mendes, A
    Merletti, F
    Nyberg, F
    Pershagen, G
    Poglabeln, H
    Riboli, E
    Schmid, G
    Simonato, L
    Trédaniel, J
    Whitley, E
    Wichmann, HE
    Winck, C
    Zambon, P
    Saracci, R
    [J]. JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1998, 90 (19) : 1440 - 1450
  • [8] Environmental tobacco smoke and pancreatic cancer: a case-control study
    Ding, Yi
    Yu, Chundong
    Han, Zenggang
    Xu, Sunyu
    Li, Dacheng
    Meng, Xiao
    Chen, Dong
    [J]. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, 2015, 8 (09): : 16729 - 16732
  • [9] EXPOSURE TO ENVIRONMENTAL TOBACCO SMOKE AND RISK OF LUNG CANCER: EVIDENCE FROM A CASE-CONTROL STUDY IN MONTREAL, CANADA
    Al-Zoughool, M.
    Pintos, J.
    Richardson, L.
    Parent, M-E
    Ghadirian, P.
    Krewski, D.
    Siemiatycki, J.
    [J]. AMERICAN JOURNAL OF EPIDEMIOLOGY, 2011, 173 : S91 - S91
  • [10] Multicenter case-control study of exposure to environmental tobacco smoke and lung cancer in Europe - Reply
    Boffetta, P
    Nyberg, F
    [J]. JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1999, 91 (09) : 803 - 804