ABROCITINIB TREATMENT IN ADOLESCENTS AND ADULTS WITH MODERATE-TO-SEVERE ATOPIC DERMATITIS: KEY EFFICACY AND SAFETY RESULTS FROM PHASE 3 TRIALS JADE MONO-1 AND JADE MONO-2

被引：0
|
作者：
Simpson, Eric L. [1 ]
Silverberg, Jonathan I. [2 ]
Forman, Seth [3 ]
Wollenberg, Andreas [4 ]
Thyssen, Jacob P. [5 ]
Flohr, Carsten [6 ]
Feeney, Claire [7 ]
Biswas, Pinaki [8 ]
DiBonaventura, Marco [9 ]
Cameron, Michael C. [10 ]
Rojo, Ricardo [11 ]
Valdez, Hernan [12 ]
机构：
[1] Oregon Hlth & Sci Univ, Dept Dermatol, Portland, OR 97201 USA
[2] George Washington Univ, Sch Med & Hlth Sci, Dept Dermatol, Washington, DC 20052 USA
[3] ForCare Clin Res, Dept Dermatol, Tampa, FL USA
[4] Ludwig Maximilian Univ Munich, Dept Dermatol, Munich, Germany
[5] Univ Copenhagen, Dept Dermatol & Allergy, Herlev & Gentofte Hosp, Hellerup, Denmark
[6] St Johns Inst Dermatol, Unit Populat Based Dermatol Res, London, England
[7] Pfizer Ltd, Global Med Affairs Inflammat & Immunol, Tadworth, Surrey, England
[8] Pfizer Inc, Biostat, New York, NY USA
[9] Pfizer Inc, Patient & Hlth Impact Inflammat & Immunol, New York, NY USA
[10] Pfizer Inc, North Amer Med Affairs Inflammat & Immunol, New York, NY USA
[11] Pfizer Inc, Global Prod Dev Inflammat & Immunol, Groton, CT 06340 USA
[12] Pfizer Inc, Global Prod Dev Inflammat & Immunol, New York, NY USA
来源：
ACTA DERMATO-VENEREOLOGICA | 2021年 / 101卷
关键词：
D O I：
暂无
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
OL10
引用
收藏
页码：13 / 14
页数：2
相关论文
共 50 条
  • [1] ABROCITINIB TREATMENT IN ADOLESCENTS AND ADULTS WITH MODERATE-TO-SEVERE ATOPIC DERMATITIS: EARLY PRURITUS RESPONSES FROM PHASE 3 TRIALS JADE MONO-1 AND JADE MONO-2
    Stander, Sonja
    Yosipovitch, Gil
    Silverberg, Jonathan I.
    Simpson, Eric L.
    Sinclair, Rodney
    Su, John C.
    Kerkmann, Urs
    Gallardo, William Romero
    Valdez, Hernan
    Rojo, Ricardo
    Biswas, Pinaki
    Farooqui, Saleem A.
    ACTA DERMATO-VENEREOLOGICA, 2021, 101 : 56 - 56
  • [2] ABROCITINIB TREATMENT IN ADOLESCENTS AND ADULTS WITH MODERATE-TO-SEVERE ATOPIC DERMATITIS: KEY EFFICACY RESULTS BY RACE AND REGION OF ENROLLMENT IN JADE MONO-2
    Cho, Sang-Hyun
    Sinclair, Rodney
    Li, Hang
    Fujita, Nobuhiro
    Freeman, Michael
    Kornmann, Oliver
    Seo, Seong-Jun
    Wang, Bo
    Fujita, Kayo
    Biswas, Pinaki
    Valdez, Hernan
    Tyring, Stephen K.
    ACTA DERMATO-VENEREOLOGICA, 2021, 101 : 56 - 56
  • [3] Efficacy and safety of abrocitinib in patients with moderate-to-severe atopic dermatitis: results from the phase III JADE MONO-2 study
    Silverberg, J.
    Simpson, E. L.
    Thyssen, J. P.
    Gooderham, M.
    Chan, G.
    Feeney, C.
    Biswas, P.
    Valdez, H.
    DiBonaventura, M.
    Nduaka, C.
    Rojo, R.
    BRITISH JOURNAL OF DERMATOLOGY, 2020, 183 (04) : E100 - E100
  • [4] Efficacy and safety of abrocitinib in patients with moderate-to-severe atopic dermatitis: results from the phase III, JADE MONO-1 study
    Simpson, E. L.
    Sinclair, R.
    Forman, S.
    Wollenberg, A.
    Asch, R.
    Cork, M.
    Bieber, T.
    Thyssen, J. P.
    Yosipovitch, G.
    Magnolo, N.
    Maari, C.
    Flohr, C.
    Feeney, C.
    Biswas, P.
    Tatulych, S.
    Valdez, H.
    Rojo, R.
    BRITISH JOURNAL OF DERMATOLOGY, 2020, 183 (04) : E105 - E106
  • [5] Examining the relationships among abrocitinib monotherapy, pruritus severity and skin clearance in patients with moderate-to-severe atopic dermatitis: results from JADE MONO-1 and JADE MONO-2
    Simpson, E. L.
    Yosipovitch, G.
    Staender, S.
    Silverberg, J. I.
    Thyssen, J. P.
    Kwatra, S. G.
    Luger, T.
    Guttman-Yassky, E.
    Tom, W. L.
    Bushmakin, A. G.
    Cappelleri, J. C.
    Chan, G.
    Feeney, C.
    Yin, N.
    Valdez, H.
    DiBonaventura, M.
    Myers, D. E.
    BRITISH JOURNAL OF DERMATOLOGY, 2021, 184 (03) : E76 - E77
  • [6] Economic impact of abrocitinib monotherapy and combination therapy in patients with moderate-to-severe atopic dermatitis: results from JADE MONO-2 and JADE COMPARE
    Gooderham, M. J.
    Chu, C. -Y.
    Rojo, R.
    Valdez, H.
    Biswas, P.
    Cameron, M. C.
    Feeney, C.
    Encinas, G. A.
    Peeples-Lamirande, K.
    Cappelleri, J. C.
    Myers, D. E.
    DiBonaventura, M.
    BRITISH JOURNAL OF DERMATOLOGY, 2021, 184 (03) : E72 - E72
  • [7] Efficacy and safety of abrocitinib in adults and adolescents with moderate-to-severe atopic dermatitis (JADE MONO-1): a multicentre, double-blind, randomised, placebo-controlled, phase 3 trial
    Simpson, Eric L.
    Sinclair, Rodney
    Forman, Seth
    Wollenberg, Andreas
    Aschoff, Roland
    Cork, Michael
    Bieber, Thomas
    Thyssen, Jacob P.
    Yosipovitch, Gil
    Flohr, Carsten
    Magnolo, Nina
    Maari, Catherine
    Feeney, Claire
    Biswas, Pinaki
    Tatulych, Svitlana
    Valdez, Hernan
    Rojo, Ricardo
    LANCET, 2020, 396 (10246): : 255 - 266
  • [8] Interpreting the relationship between pruritus and quality of life in patients with moderate-to-severe atopic dermatitis: a post-hoc analysis of JADE MONO-1 and JADE MONO-2
    Gooderham, M. J.
    Yosipovitch, G.
    Stander, S.
    Fonacier, L.
    Szepietowski, J. C.
    Deleuran, M.
    Girolomoni, G.
    Bushmakin, A. G.
    Cappelleri, J. C.
    Watkins, M.
    Feeney, C.
    Valdez, H.
    Rojo, R.
    DiBonaventura, M.
    Myers, D. E.
    BRITISH JOURNAL OF DERMATOLOGY, 2021, 185 (03) : E139 - E140
  • [9] Efficacy of abrocitinib monotherapy in patients with prior exposure to systemic treatments: pooled results from the JADE MONO-1 and JADE MONO-2 studies
    Ameen, M.
    Chiu, W. Sin
    Rojo, R.
    Biswas, P.
    Romero, W.
    Ardern-Jones, M.
    BRITISH JOURNAL OF DERMATOLOGY, 2021, 185 : 11 - 11
  • [10] Efficacy and safety of abrocitinib in adolescents with moderate-to-severe atopic dermatitis from the JADE clinical trial program
    Eichenfield, Lawrence F.
    Flohr, Carsten
    Bangert, Christine
    Irvine, Alan D.
    Weidinger, Stephan
    Nesnas, John
    Koppensteiner, Herwig
    Zhang, Fan
    Rojo, Ricardo
    Chan, Gary
    BRITISH JOURNAL OF DERMATOLOGY, 2023, 188
12345