Selective detection of HSO3- in living cells using a pyrroloquinoline structure containing turn-on fluorescent probe

被引：0

作者：

Zhou, Jiahua ^{[1
]}

Wang, Fa ^{[1
]}

Xu, Yuan-Xiang ^{[1
]}

Gu, Xue-Fang ^{[1
]}

Shi, Yu-Jun ^{[1
]}

Yang, Bing ^{[1
]}

机构：

[1] Nantong Univ, Sch Chem & Chem Engn, Nantong 226019, Peoples R China

来源：

ANALYTICAL SCIENCES | 2022年 / 38卷 / 08期

关键词：

HSO3-; detection; Fluorescent probe; High selectivity; Biological imaging; Michael addition reaction; SO2; DERIVATIVES; RAPID DETECTION; MITOCHONDRIA; BISULFITE;

D O I：

10.1007/s44211-022-00126-2

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A turn-on fluorescence probe PQP-1 with a pyrroloquinoline skeleton has been designed and synthesized. Probe PQP-1 showed high sensitivity to HSO3-, low detection limit (16.83 nM), and a wide linear range (50-3000 RM). More importantly, probe PQP-1 could distinguish between HSO3- and SO32-. Furthermore, cell imaging experiments of HSO3- in HeLa cells revealed that probe PQP-1 had potential application value in biological systems.

引用

页码：1033 / 1038

页数：6

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