Pilot Phase I/II Clinical Trial with Autologous Mesenchymal Stem Cells in Patients with Multiple Sclerosis and Amyotrophic Lateral Sclerosis

被引:0
|
作者
Karussis, D. [1 ,2 ,3 ]
Karageorgiou, C. [4 ]
Gowda-Kurkalli, B. [5 ]
Kassis, I. [1 ,2 ,3 ]
Vaknin-Dembinsky, A. [1 ,2 ,3 ]
Gomori, J. M. [6 ]
Bulte, J. [7 ,8 ]
Petrou, P. [1 ,2 ,3 ]
Ben-Hur, T. [1 ,2 ,3 ]
Slavin, S. [5 ]
机构
[1] Hadassah Hebrew Univ Hosp, Dept Neurol, Lab Neuroimmunol, IL-91120 Jerusalem, Israel
[2] Hadassah Hebrew Univ Hosp, Agnes Ginges Ctr Neurogenet, IL-91120 Jerusalem, Israel
[3] Hadassah Hebrew Univ Hosp, Multiple Sclerosis Ctr, IL-91120 Jerusalem, Israel
[4] Gennimatas Gen Hosp, Dept Neurol, Athens, Greece
[5] Int Ctr Cell Therapy & Canc Immunotherapy CTCI, IL-64239 Tel Aviv, Israel
[6] Hadassah Hebrew Univ Hosp, Dept Radiol, Unit Neuroradiol, IL-91120 Jerusalem, Israel
[7] Johns Hopkins Univ, Sch Med, Dept Biomed Engn, Russell H Morgan Dept Radiol & Radiol Sci, Baltimore, MD 21205 USA
[8] Johns Hopkins Univ, Sch Med, Dept Chem & Biomol Engn, Baltimore, MD 21205 USA
关键词
D O I
暂无
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
引用
收藏
页码:650 / 650
页数:1
相关论文
共 50 条
  • [1] Pilot Phase I/II Clinical Trial with Autologous Mesenchymal Stem Cells in Patients with Multiple Sclerosis and Amyotrophic Lateral Sclerosis
    Karussis, Dimitrias
    Karageorgiou, Clementine
    Gowda-Kurkalli, Basan
    Vaknin-Dembinsky, Adi
    Gomori, John Moshe
    Kassis, Ibrahim
    Petrou, Panayiota
    Bulte, Jeff
    Slavin, Shimon
    NEUROLOGY, 2010, 74 (09) : A295 - A295
  • [2] Pilot phase I/II clinical trial with autologous mesenchymal stem cells in patients with multiple sclerosis
    Karussis, D.
    Slavin, S.
    Karageorgiou, C.
    Kassis, I.
    Vaknin-Dembinski, A.
    Petrou, P.
    Gomori, J.
    Gowda-Kurkalli, B.
    Ben-Hur, T.
    Bulte, J.
    HUMAN GENE THERAPY, 2010, 21 (10) : 1436 - 1436
  • [3] A phase II clinical trial with repeated intrathecal injections of autologous mesenchymal stem cells in patients with amyotrophic lateral sclerosis
    Petrou, Panayiota
    Kassis, Ibrahim
    Yaghmour, Nour Eddine
    Ginzberg, Ariel
    Karussis, Dimitrios
    FRONTIERS IN BIOSCIENCE-LANDMARK, 2021, 26 (10): : 693 - 706
  • [4] Autologous Stem Cells Transplantation in Amyotrophic Lateral Sclerosis: A Phase I Clinical Trial
    Mazzini, Letizia
    Ferrero, Iuana
    Testa, Lucia
    Mareschi, Katia
    Luparello, Vincenzo
    Miglioretti, Massimo
    Stecco, Alessandro
    Oggioni, Gaia Donata
    Monaco, Francesco
    Fagioli, Franca
    NEUROLOGY, 2009, 72 (11) : A363 - A363
  • [5] Analysis of patients with amyotrophic lateral sclerosis (ALS) treated with autologous differentiated mesenchymal stem cells: a phase I/II and IIa clinical trial
    Karussis, D.
    Petrou, P.
    Offen, D.
    Argov, Z.
    Goudkin, M.
    Levi, Y.
    Gothelf, Y.
    Kassis, I.
    Dembinski, A. Vaknin
    Ben Hur, T.
    Melamed, E.
    JOURNAL OF NEUROLOGY, 2014, 261 : S47 - S48
  • [6] Analysis of patients with amyotrophic lateral sclerosis (ALS) treated with autologous differentiated mesenchymal stem cells: a phase I/II and IIa clinical trial
    Karussis, D.
    Petrou, P.
    Offen, D.
    Argov, Z.
    Goudkin, M.
    Levi, Y.
    Gothelf, Y.
    Kassis, I.
    Dembinski, A. Vaknin
    Ben Hur, T.
    Melamed, E.
    EUROPEAN JOURNAL OF NEUROLOGY, 2014, 21 : 63 - 63
  • [7] PHASE I/II CLINICAL TRIAL OF INTRAMUSCULAR IMPLANTATION OF AUTOLOGOUS BONE MARROW STEM CELLS IN AMYOTROPHIC LATERAL SCLEROSIS PATIENTS
    Cano, R.
    Martin, C.
    Pastore, C.
    Blanquer, M.
    Iniesta, P.
    Gomez-Espuch, J.
    Pena, M. A.
    Moraleda, J. M.
    BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2012, 111 : 40 - 40
  • [8] Treatment of amyotrophic lateral sclerosis (ALS) with autologous differentiated mesenchymal stem cells: preliminary results of a phase I/II clinical trial in 12 patients
    Karussis, D.
    Petrou, P.
    Offen, D.
    Gothelf, Y.
    Levy, Y.
    Argov, Z.
    Gotkine, M.
    Vaknin-Dembinsky, A.
    Kassis, I.
    Ben Hur, T.
    Melamed, E.
    JOURNAL OF NEUROLOGY, 2013, 260 : S22 - S23
  • [9] Mesenchymal stem cell (MSC) transplantation in patients with amyotrophic lateral sclerosis: phase I/II clinical trial
    Czaplinski, A.
    Wojtkiewicz, J.
    Siwek, T.
    Habich, A.
    Barczewska, M.
    Maksymowicz, W.
    EUROPEAN JOURNAL OF NEUROLOGY, 2015, 22 : 738 - 738
  • [10] Autologous mesenchymal stem cells: Clinical application in amyotrophic lateral sclerosis
    Fagioli, F
    Mareschi, K
    Ferrero, I
    Rustichelli, D
    Venturi, C
    Pastore, I
    Vassallo, E
    Mazzini, L
    CYTOMETRY PART A, 2006, 69A (05) : 471 - 472