Spirostanol Saponins from the Fibrous Roots of Ophiopogon japonicus (THUNB.) KER-GAWL

被引：21
|
作者：
Duan, Chang-Ling [1 ,2 ]
Li, Yu-Juan [2 ]
Li, Peng [2 ]
Jiang, Yong [1 ]
Liu, Jian-Xun [2 ]
Tu, Peng-Fei [1 ]
机构：
[1] Peking Univ, Sch Pharmaceut Sci, Beijing 100191, Peoples R China
[2] China Acad Chinese Med Sci, Xiyuan Hosp, Beijing 100091, Peoples R China
来源：
HELVETICA CHIMICA ACTA | 2010年 / 93卷 / 02期
关键词：
GLYCOSIDES; TUBER; HOMOISOFLAVONOIDS;
D O I：
10.1002/hlca.200900165
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Three new steroidal saponins, (25R)-ruscogenin-3-yl alpha-L-rhamnopyranosyl-(1 -> 2)-[beta-D-xylopyranosyl-(1 -> 4)]-beta-D-glucopyranoside (1). diosgenin-3-yl 2-O-acetyl-alpha-L-rhamnopyranosyl-(1 -> 2)-[beta-D-xylopyranosyl-(1 -> 4)]-beta-D-glucopyranoside (2), and pennogenin-3-yl 2-O-acetyl-alpha-L-rhamnopyranosyl-(1 -> 2)-[beta-D-glucopyranoside-(1 -> 4)]-beta-D-glucopyranoside (3) were isolated from the fibrous roots of Ophiopogon japonicus (THUNB.) KER-GAWL. Their structures were determined by spectroscopic methods including IR, HR-ESI-MS, and 1D- and 2D-NMR. All of these three steroidal saponins exhibited weak cytotoxicities against Hela and Hep2 cell lines.
引用
收藏
页码：227 / 232
页数：6
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