The presence of macroprolactinaemia was investigated in the symptom-free hyperprolactinaemia cases to reveal its incidence. The serum prolactin (PRL) fractions in 21 female patients with hyperprolactinaemia without any clinical symptoms were analyzed with PEG (polyethylene glycol precipitation) procedure. In 14 of these 21 cases, hyperprolactinaemia was detected with a high fraction of macroprolactin. In cases with asymptomatic hyperprolactinaemia, it is more appropriate to employ the PEG precipitation test to detect the disorder. High levels of serum prolactin, do not essentially indicate the presence of a prolactinoma but may only indicate macroprolactinaemia. (C) 2004 Elsevier Ireland Ltd. All rights reserved.
机构:
Manchester Royal Infirm, Dept Endocrinol, Manchester M13 9WL, Lancs, EnglandManchester Royal Infirm, Dept Endocrinol, Manchester M13 9WL, Lancs, England
Prabhakar, V. K. B.
Davis, J. R. E.
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Manchester Royal Infirm, Dept Endocrinol, Manchester M13 9WL, Lancs, EnglandManchester Royal Infirm, Dept Endocrinol, Manchester M13 9WL, Lancs, England
Davis, J. R. E.
BEST PRACTICE & RESEARCH IN CLINICAL OBSTETRICS & GYNAECOLOGY,
2008,
22
(02):
: 341
-
353
机构:
Uniwersytet Med Lublinie, Katedra & Klin Rozrodczosci & Androl, Lublin, PolandUniwersytet Med Lublinie, Katedra & Klin Rozrodczosci & Androl, Lublin, Poland
Tkaczuk-Wlach, Joanna
Sobstyl, Malgorzata
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Uniwersytet Med Lublinie, Katedra & Klin Rozrodczosci & Androl, Lublin, PolandUniwersytet Med Lublinie, Katedra & Klin Rozrodczosci & Androl, Lublin, Poland
Sobstyl, Malgorzata
Cholubek-Robak, Dorota
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Uniwersytet Med Lublinie, Katedra & Klin Rozrodczosci & Androl, Lublin, PolandUniwersytet Med Lublinie, Katedra & Klin Rozrodczosci & Androl, Lublin, Poland
Cholubek-Robak, Dorota
Jakiel, Grzegorz
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机构:
Uniwersytet Med Lublinie, Katedra & Klin Rozrodczosci & Androl, Lublin, Poland
CMKP Warszawie, Klin Poloznictwa & Ginekol 1, Warsaw, PolandUniwersytet Med Lublinie, Katedra & Klin Rozrodczosci & Androl, Lublin, Poland
机构:
Manchester Royal Infirm, Dept Endocrinol, Manchester M13 9WL, Lancs, EnglandManchester Royal Infirm, Dept Endocrinol, Manchester M13 9WL, Lancs, England
Demssie, Yared N.
Davis, Julian R. E.
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机构:
Manchester Royal Infirm, Dept Endocrinol, Manchester M13 9WL, Lancs, England
Univ Manchester, Endocrine Sci Res Grp, Manchester M13 9PL, Lancs, EnglandManchester Royal Infirm, Dept Endocrinol, Manchester M13 9WL, Lancs, England