Docosahexaenoic Acid Supplementation Abrogated Fibrotic Progression in Nonalcoholic Steatohepatitis By Suppressing Activation of Hepatic Stellate Cells through GPR91

被引：0
|
作者：
Liu, Xuejing [1 ]
Niu, Chen [1 ]
Wu, Jian [2 ]
机构：
[1] Fudan Univ, Sch Basic Med Sci, Dept Med Microbiol, Shanghai, Peoples R China
[2] Fudan Univ, Shanghai Med Coll, Shanghai Inst Liver Dis, Shanghai, Peoples R China
来源：
HEPATOLOGY | 2018年 / 68卷
关键词：
D O I：
暂无
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
741
引用
收藏
页码：441A / 441A
页数：1
相关论文
共 35 条
  • [1] Succinate causes α-SMA production through GPR91 activation in hepatic stellate cells
    Li, Ying Hui
    Woo, Sung Hoon
    Choi, Dae Hee
    Cho, Eun-Hee
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2015, 463 (04) : 853 - 858
  • [2] SUPPRESSING MASH FIBROTIC PROGRESSION BY BLOCKING SUCCINATE-GPR91 SIGNALING AXIS IN HEPATIC STELLATE CELLS
    Wu, Jian
    Xie, Li
    Chen, Hui
    Zhang, Li
    Yang, Yong-Yu
    Liu, Xiu-Ping
    HEPATOLOGY, 2024, 80 : S1539 - S1540
  • [3] Metformin ameliorates activation of hepatic stellate cells and hepatic fibrosis by succinate and GPR91 inhibition
    Giang Nguyen
    Park, So Young
    Cong Thuc Le
    Park, Won Sun
    Choi, Dae Hee
    Cho, Eun-Hee
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 495 (04) : 2649 - 2656
  • [4] SUPPRESSING CHOLESTATIC FIBROTIC PROGRESSION BY TARGETING JCAD IN HEPATIC STELLATE CELLS
    Xie, Li
    Chen, Hui
    Zhou, Yuan
    Zhang, Li
    Yang, Yongyu
    Liu, Xiuping
    Wu, Jian
    HEPATOLOGY, 2023, 78 : S2074 - S2075
  • [5] SECRETOME OF SENESCENT HEPATIC STELLATE CELLS FAVORS MALIGNANT TRANSFORMATION FROM NONALCOHOLIC STEATOHEPATITIS-FIBROTIC PROGRESSION TO HEPATOCELLULAR CARCINOMA
    Zhou, Yuan
    Zhang, Li
    Ma, Yue
    Xie, Li
    Yang, Yongyu
    Jin, Cheng
    Chen, Hui
    Ding, Jia
    Wu, Jian
    HEPATOLOGY, 2023, 78 : S1529 - S1530
  • [6] Secretome of senescent hepatic stellate cells favors malignant transformation from nonalcoholic steatohepatitis-fibrotic progression to hepatocellular carcinoma
    Zhou, Yuan
    Zhang, Li
    Ma, Yue
    Xie, Li
    Yang, Yong-Yu
    Jin, Cheng
    Chen, Hui
    Zhou, Ying
    Song, Guang-Qi
    Ding, Jia
    Wu, Jian
    THERANOSTICS, 2023, 13 (13): : 4430 - 4448
  • [7] Lactate transporter MCT1 in hepatic stellate cells promotes fibrotic collagen expression in nonalcoholic steatohepatitis
    Min, Kyounghee
    Yenilmez, Batuhan
    Kelly, Mark
    Echeverria, Dimas
    Elleby, Michael
    Lifshitz, Lawrence M.
    Raymond, Naideline
    Tsagkaraki, Emmanouela
    Harney, Shauna M.
    DiMarzio, Chloe
    Wang, Hui
    McHugh, Nicholas
    Bramato, Brianna
    Morrison, Brett
    Rothstein, Jeffery D.
    Khvorova, Anastasia
    Czech, Michael P.
    ELIFE, 2024, 12
  • [8] The mechanism of increased intestinal palmitic acid absorption and its impact on hepatic stellate cell activation in nonalcoholic steatohepatitis
    Masakazu Hanayama
    Yasunori Yamamoto
    Hiroki Utsunomiya
    Osamu Yoshida
    Shuang Liu
    Masaki Mogi
    Bunzo Matsuura
    Eiji Takeshita
    Yoshiou Ikeda
    Yoichi Hiasa
    Scientific Reports, 11
  • [9] The mechanism of increased intestinal palmitic acid absorption and its impact on hepatic stellate cell activation in nonalcoholic steatohepatitis
    Hanayama, Masakazu
    Yamamoto, Yasunori
    Utsunomiya, Hiroki
    Yoshida, Osamu
    Liu, Shuang
    Mogi, Masaki
    Matsuura, Bunzo
    Takeshita, Eiji
    Ikeda, Yoshiou
    Hiasa, Yoichi
    SCIENTIFIC REPORTS, 2021, 11 (01)
  • [10] A porcine placental extract alleviates lipotoxicity-induced steatohepatitis by suppressing activation of hepatic macrophages and stellate cells
    Ota, T.
    Xu, L.
    Chen, G.
    Nagashimada, M.
    DIABETOLOGIA, 2018, 61 : S569 - S569
1234