Post-acute COVID-19 syndrome

Post-acute COVID-19 syndrome (PACS) includes the subacute, symptomatic phase 4-12 weeks after acute COVID-19 as well as the subsequent chronic post-COVID-19 period. PACS is associated with various general symptoms and organ (pulmonary, cardiovascular, neuropsychiatric, endocrine, musculoskeletal, dermatological, renal) manifestations. In this summary, we review the pathogenetic and risk factors leading to the development of PACS. We present the clinical picture and diagnostics. PACS should usually be managed by the general practitioner. The management of PACS includes pharmacological and non-pharmacological treatment, multidisciplinary rehabilitation and regular follow-ups. Here we also discuss the tasks of the general practitioner, the reasons for referral to specialists and the need to set up and operate a post-COVID-19 network.