Fatal vancomycin- and linezolid-resistant Enterococcus faecium sepsis in a child undergoing allogeneic haematopoietic stem cell transplantation for beta-thalassaemia major

被引:10
|
作者
Fossati, Marco [1 ]
Cappelli, Barbara [1 ,2 ]
Biral, Erika [1 ,2 ]
Chiesa, Robert [1 ,2 ]
Biffi, Alessandra [1 ,2 ]
Ossi, Cristina [3 ]
Moro, Matteo [4 ]
Cirillo, Daniela Maria [5 ]
Clementi, Massimo [3 ,6 ]
Soliman, Clara [1 ]
Ciceri, Fabio [1 ]
Roncarolo, Maria Grazia [1 ,2 ,6 ]
Fumagalli, Luca [7 ]
Marktel, Sarah [1 ,2 ]
机构
[1] Ist Sci San Raffaele, Pediat Immunohematol & Bone Marrow Transplantat U, I-20132 Milan, Italy
[2] San Raffaele Telethon Inst Gene Therapy HSR TIGET, Milan, Italy
[3] Ist Sci San Raffaele, Microbiol Lab, I-20132 Milan, Italy
[4] Ist Sci San Raffaele, Chief Med Off, I-20132 Milan, Italy
[5] Ist Sci San Raffaele, Emerging Bacterial Pathogens Unit, I-20132 Milan, Italy
[6] Univ Vita Salute San Raffaele, Sch Med, Milan, Italy
[7] Ist Sci San Raffaele, Dept Infect Dis, I-20132 Milan, Italy
关键词
INFECTIONS; EMERGENCE; THERAPY;
D O I
10.1099/jmm.0.018598-0
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Recently vancomycin-resistant and sporadically linezolid-resistant Enterococcus species have been described in adults. We report what we believe to be the first case of a child with prolonged bone marrow aplasia following haematopoietic stem cell transplantation developing a fatal sepsis caused by Enterococcus faecium resistant to glycopeptides and linezolid.
引用
收藏
页码:839 / 842
页数:4
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