Ultrastructural and cytochemical changes in the respiratory compartment of the lungs in rats after combined treatment with fine silicon dioxide powder and uridine

被引：1

作者：

Lebkova, NP ^{[1
]}

Baranov, VI ^{[1
]}

机构：

[1] Russian Med Acad Postgrad Educ, Moscow, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2004年 / 137卷 / 06期

关键词：

silicon dioxide; lungs; uridine; electron microscopy;

D O I：

10.1023/B:BEBM.0000042710.84974.b0

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Electron microscopy and cytochemical study of alveolar tissue of rat lungs were performed at the early stage after intratracheal treatment with fine silicon dioxide powder. The preparation was administered to animals receiving or not receiving intravenous injection of uridine. Dust particles permeated the cytoplasm, mitochondria, and nuclei of cells in the air-blood barrier of the alveoli. Uridine decreased the severity of dust-induced damage to cells and increased intracellular glycogen content.

引用

页码：556 / 559

页数：4