Bone Tissue Engineering: Natural Origination Or Synthetic Polymeric Scaffolds?

被引:1
|
作者
Danti, Serena [1 ,4 ]
Lisanti, Michele [2 ]
Berrettini, Stefano [3 ]
Petrini, Mario [1 ,4 ]
Pietrabissa, Andrea [1 ]
机构
[1] Univ Pisa, Dept Oncol Transplantat & New Technol Med, Via Roma 55, I-56126 Pisa, Italy
[2] Univ Pisa, Ind Med, Dept Endocrinol & Metabolism Orthoped & Traumatol, I-56124 Pisa, Italy
[3] Univ Pisa, Dept Neurosci, ENT Unit, I-56124 Pisa, Italy
[4] Univ Pisa, CUCCS, I-56126 Pisa, Italy
关键词
Cancellous Bone Grafts; Demineralized Bone Matrix; Mesenchymal Stem Cells; Polymeric Scaffolds; Bone Tissue Engineering;
D O I
10.4028/www.scientific.net/AMR.15-17.65
中图分类号
O414.1 [热力学];
学科分类号
摘要
The aim of this report was to investigate the behavior of human mesenchymal stem cells (hMSCs) when cultured on different porous 3D scaffolds, having natural or synthetic origination. Natural scaffolds were obtained by hand made processing of human bone tissue (allograft), because its well known osteoconductive features, using different procedures to eliminate the donor cellular phase. Cancellous bone was frozen, heated or demineralized before being loaded with hMSCs. Among the variety of synthetic materials, biodegradable polymeric spongy matrices were chosen and comparatively tested as scaffolds for hMSCs growth.
引用
收藏
页码:65 / 70
页数:6
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