Recent progress in the synthesis of six-membered aminocyclitols (2008-2017)

被引：9
|
作者：
Donaldson, William A. [1 ]
机构：
[1] Marquette Univ, Dept Chem, POB 1881, Milwaukee, WI 53226 USA
来源：
ARKIVOC | 2018年
关键词：
Aminocyclitols; stereoselective synthesis; ring-closing metathesis; cyclizations; chiral pool; ORTHOGONALLY PROTECTED 2-DEOXYSTREPTAMINE; CONVENIENT SYNTHESIS; STEREOSELECTIVE-SYNTHESIS; SINGLET OXYGEN; DERIVATIVES; (+)-VALIENAMINE; VALIENAMINE; VALIOLAMINE; CONCISE; (-)-1-EPI-VALIOLAMINE;
D O I：
10.24820/ark.5550190.p010.450
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Aminocyclitols are of interest as glucosidase inhibitors, as probes for the study of pseudoglycosyltransferases, and as potential therapeutics for the treatment of Gaucher's disease. The synthesis of these targets was reviewed in early 2008, and the aim of this review is to cover material relevant to the synthesis of aminocyclitols since that time. While not a focus of this review, biological evaluation of compounds will be presented where it is recorded in the literature. [GRAPHICS] .
引用
收藏
页码：231 / 256
页数：26
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