CIRCULAR RNA - MIRNA MEDIATED INTERACTION IN MYOCARDIAL INFARCTION

被引：0

作者：

Doneva, Yordanka ^{[1
,2
]}

Valkov, Veselin ^{[1
,4
]}

Kashlov, Yavor ^{[1
,2
]}

Mihaylova, Galya ^{[3
]}

Angelov, Atanas ^{[2
,4
]}

Radanova, Maria ^{[3
]}

机构：

[1] Med Univ Varna, Dept Propedeut Internal Med, Varna, Bulgaria

[2] UMHAT St Marina, Dept Internal Med, Varna, Bulgaria

[3] Med Univ Varna, Dept Biochem Mol Med & Nutrigen, Varna, Bulgaria

[4] UMHAT St Marina, Clin Cardiol 1, Varna, Bulgaria

来源：

JOURNAL OF IMAB | 2021年 / 27卷 / 02期

关键词：

CircRNAs; miRNAs; myocardial infarction; UP-REGULATION; BIOGENESIS; BIOMARKERS; PROTECTS; FIBROSIS; INJURY; ROLES; HEART;

D O I：

10.5272/jimab.2021272.3793

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Circular RNA (circRNAs) belong to the long non-coding RNA family, but unlike the linear RNA in circular RNA, the 3' and 5' end in the RNA molecule are joined together, forming their circular structure. Until recently, circRNAs have been believed to be a side product of splicing, but now it is known that they have a wide range of biological functions, from regulators of gene expression to regulators of other non-coding RNAs - microRNAs (miRNAs). CircRNAs have the potential of being therapeutic targets and biomarkers for diseases. There are little data and only several investigations about this type of RNAs in myocardial infarction in humans. This review summarizes the role of some new circRNA - miRNA interactions in the development of Myocardial Infarction.

引用

页码：3793 / 3798

页数：6

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