Limited fertility of the subcutaneous cysts of Echinococcus multilocularis

被引:0
|
作者
Dang, Z. [1 ,2 ,3 ,4 ]
Zhang, X. [5 ]
Luo, X. [5 ]
Gao, Z. [5 ]
Jia, W. [5 ]
Xiao, N. [1 ,2 ,3 ,4 ]
Huang, F. [6 ]
Zhao, Y. [7 ]
Xu, S. [1 ,2 ,3 ,4 ,7 ]
Hu, W. [1 ,2 ,3 ,4 ]
Zheng, Y. [5 ,8 ]
机构
[1] Minist Hlth, Key Lab Biol Parasite & Vector, Shanghai, Peoples R China
[2] Natl Ctr Int Res Trop Dis, Shanghai, Peoples R China
[3] WHO Collaborating Ctr Trop Dis, Shanghai, Peoples R China
[4] Chinese Ctr Dis Control & Prevent, Natl Inst Parasit Dis, Shanghai 200025, Peoples R China
[5] CAAS, Lanzhou Vet Res Inst, Key Lab Vet Parasitol Gansu Prov, State Key Lab Vet Etiol Biol, Lanzhou 730046, Gansu, Peoples R China
[6] Tottori Univ, Fac Agr, Sch Vet Med, Parasitol Lab, Tottori 6808553, Japan
[7] Guilin Med Univ, Coll Biotechnol, Dept Biomed Engn, Guilin 541004, Guangxi, Peoples R China
[8] Jiangsu Coinnovat Ctr Prevent & Control Important, Yangzhou 225009, Jiangsu, Peoples R China
基金
中国国家自然科学基金;
关键词
ALVEOLAR ECHINOCOCCOSIS;
D O I
暂无
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
Echinococcus multilocularis is a tiny devastating worm that causes alveolar echinococcosis in humans. This disease mainly occurs in the liver but rarely in other organs. We report the subcutaneous encystment of E. multilocularis metacestodes in experimentally infected mice. Subcutaneous cysts had remarkably fewer protoscoleces (2.05 +/- 1.47, n = 20) and small irregular-shape vesicles (ISVs) in the lumen as compared to liver cysts (69.6 +/- 55.65, n = 10). Moreover, abnormal development of a protoscolex was also observed in a subcutaneous cyst. The results suggest that subcutaneous encystment may have potential adverse effects on the reproductivity and development of protoscoleces, providing potential explanations for high tissue preference of metacestode encystment.
引用
收藏
页码:491 / 493
页数:3
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