Relationship between Osteoinductive Characteristics of Biocomposite Material and Physicochemical Characteristics of Coating

被引：6

作者：

Fedorova, M. Z. ^{[1
]}

Nadezhdin, S. V. ^{[1
]}

Kolobov, Yu. R. ^{[1
]}

Ivanov, M. B. ^{[1
]}

Pavlov, N. A. ^{[1
]}

Zubareva, E. V. ^{[1
]}

机构：

[1] Belgorod State Univ, Belgorod, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2009年 / 148卷 / 05期

关键词：

hydroxyapatite; implant; osteoconduction; osteoinduction;

D O I：

10.1007/s10517-010-0826-2

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

The osteoinductive characteristics of hydroxylapatite-based coating with different physicochemical characteristics were studied. The formation of the bone tissue on the studied types of the implant coating differed by the pattern and rate of formation of structural elements of the bone. Clear-cut phase-wise osteogenesis was seen on combined calcium phosphate coating: intense formation of the fibrous interstitial substance ( due to cellular structure of hydroxylapatite) and slow maturing of cell elements. Bilayer composite coating provided ( during the same period) the formation of more mature connective tissue. This phenomenon can be explained by better bioavailability of the coating material. The properties of combined calcium phosphate coating can be evaluated as mainly osteoconductive, while those of bilayer composite coating as osteoinductive.

引用

页码：822 / 824

页数：3

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